Loading…
Comparative analysis of the pulmonary microbiome in healthy and diseased pigs
The lungs possess an effective antimicrobial system and a strong ability to eliminate microorganisms in healthy organisms, and were once considered sterile. With the development of culture-independent sequencing technology, the richness and diversity of porcine lung microbiota have been gaining atte...
Saved in:
| Published in: | Molecular genetics and genomics : MGG 2021, Vol.296 (1), p.21-31 |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c375t-a6b034311d36ebf5305f421937769ebb27ab5352d387641c4f83ad55d1cd1fe83 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c375t-a6b034311d36ebf5305f421937769ebb27ab5352d387641c4f83ad55d1cd1fe83 |
| container_end_page | 31 |
| container_issue | 1 |
| container_start_page | 21 |
| container_title | Molecular genetics and genomics : MGG |
| container_volume | 296 |
| creator | Li, Zongjie Wang, Xin Di, Di Pan, Ruyi Gao, Yun Xiao, Changguang Li, Beibei Wei, Jianchao Liu, Ke Qiu, Yafeng Ma, Zhiyong |
| description | The lungs possess an effective antimicrobial system and a strong ability to eliminate microorganisms in healthy organisms, and were once considered sterile. With the development of culture-independent sequencing technology, the richness and diversity of porcine lung microbiota have been gaining attention. In order to study the relationship between lung microbiota and porcine respiratory disease complex (PRDC), the lung microbiota in healthy and diseased swine bronchoalveolar lavage fluids were analyzed and compared using the Illumina MiSeq sequencing platform. The predominant microbial communities of healthy and diseased swine were similar at the phylum level, mainly composed of Proteobacteria, Firmicutes, Tenericutes, and Bacteroidetes. However, the bacterial taxonomic communities of healthy and diseased swine differed at the genus level. The higher relative abundances of
Lactococcus
,
Enterococcus
,
Staphylococcus,
and
Lactobacillus
genera in healthy swine might provide more benefits for lung health, while the enhanced richness of
Streptococcus
,
Haemophilus
,
Pasteurella,
and
Bordetella
genera in diseased swine might be closely related to pathogen invasion and the occurrence of respiratory disease. In conclusion, the observed differences in the richness and diversity of lung microbiota can provide novel insights into their relationship with PRDC. Analyses of swine lung microbiota communities might produce an effective strategy for the control and prevention of respiratory tract infections. |
| doi_str_mv | 10.1007/s00438-020-01722-5 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2444383323</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2481412095</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-a6b034311d36ebf5305f421937769ebb27ab5352d387641c4f83ad55d1cd1fe83</originalsourceid><addsrcrecordid>eNp9kE1LAzEURYMotlb_gAsJuHEzmuQlk-lSil-guNF1yEwybcp8mcwI_femTq3gwlUe5Lz7uAehc0quKSHyJhDCIUsIIwmhkrFEHKApTalMeMrgcD9TMUEnIaxJpFImj9EE2JxzmWVT9LJo60573btPi3Wjq01wAbcl7lcWd0NVt432G1y7wre5a2uLXYNXVlf9ahN5g40LVgdrcOeW4RQdlboK9mz3ztD7_d3b4jF5fn14Wtw-JwVI0Sc6zQlwoNRAavNSABElZ3QOUqZzm-dM6lyAYAYymXJa8DIDbYQwtDC0tBnM0NWY2_n2Y7ChV7ULha0q3dh2CIpxHs0AMIjo5R903Q4-Ft1SGeWUkbmIFBupWDMEb0vVeVfH5ooStZWtRtkqylbfstV26WIXPeS1NfuVH7sRgBEI8atZWv97-5_YLxOHiOM</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2481412095</pqid></control><display><type>article</type><title>Comparative analysis of the pulmonary microbiome in healthy and diseased pigs</title><source>Springer Link</source><creator>Li, Zongjie ; Wang, Xin ; Di, Di ; Pan, Ruyi ; Gao, Yun ; Xiao, Changguang ; Li, Beibei ; Wei, Jianchao ; Liu, Ke ; Qiu, Yafeng ; Ma, Zhiyong</creator><creatorcontrib>Li, Zongjie ; Wang, Xin ; Di, Di ; Pan, Ruyi ; Gao, Yun ; Xiao, Changguang ; Li, Beibei ; Wei, Jianchao ; Liu, Ke ; Qiu, Yafeng ; Ma, Zhiyong</creatorcontrib><description>The lungs possess an effective antimicrobial system and a strong ability to eliminate microorganisms in healthy organisms, and were once considered sterile. With the development of culture-independent sequencing technology, the richness and diversity of porcine lung microbiota have been gaining attention. In order to study the relationship between lung microbiota and porcine respiratory disease complex (PRDC), the lung microbiota in healthy and diseased swine bronchoalveolar lavage fluids were analyzed and compared using the Illumina MiSeq sequencing platform. The predominant microbial communities of healthy and diseased swine were similar at the phylum level, mainly composed of Proteobacteria, Firmicutes, Tenericutes, and Bacteroidetes. However, the bacterial taxonomic communities of healthy and diseased swine differed at the genus level. The higher relative abundances of
Lactococcus
,
Enterococcus
,
Staphylococcus,
and
Lactobacillus
genera in healthy swine might provide more benefits for lung health, while the enhanced richness of
Streptococcus
,
Haemophilus
,
Pasteurella,
and
Bordetella
genera in diseased swine might be closely related to pathogen invasion and the occurrence of respiratory disease. In conclusion, the observed differences in the richness and diversity of lung microbiota can provide novel insights into their relationship with PRDC. Analyses of swine lung microbiota communities might produce an effective strategy for the control and prevention of respiratory tract infections.</description><identifier>ISSN: 1617-4615</identifier><identifier>EISSN: 1617-4623</identifier><identifier>DOI: 10.1007/s00438-020-01722-5</identifier><identifier>PMID: 32944788</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject><![CDATA[Alveoli ; Animal Genetics and Genomics ; Animals ; Biochemistry ; Biomedical and Life Sciences ; Bordetella - classification ; Bordetella - genetics ; Bordetella - isolation & purification ; Bordetella - pathogenicity ; Bronchoalveolar Lavage Fluid - microbiology ; Bronchus ; Comparative analysis ; DNA, Bacterial - genetics ; Enterococcus - classification ; Enterococcus - genetics ; Enterococcus - isolation & purification ; Genera ; Haemophilus - classification ; Haemophilus - genetics ; Haemophilus - isolation & purification ; Haemophilus - pathogenicity ; High-Throughput Nucleotide Sequencing ; Human Genetics ; Lactobacillus - classification ; Lactobacillus - genetics ; Lactobacillus - isolation & purification ; Lactococcus - classification ; Lactococcus - genetics ; Lactococcus - isolation & purification ; Life Sciences ; Lung - microbiology ; Lung diseases ; Microbial Genetics and Genomics ; Microbiomes ; Microbiota ; Microbiota - genetics ; Original Article ; Pasteurella - classification ; Pasteurella - genetics ; Pasteurella - isolation & purification ; Pasteurella - pathogenicity ; Phylogeny ; Plant Genetics and Genomics ; Respiration ; Respiratory diseases ; Respiratory tract diseases ; Respiratory Tract Infections - microbiology ; RNA, Ribosomal, 16S - genetics ; Staphylococcus - classification ; Staphylococcus - genetics ; Staphylococcus - isolation & purification ; Streptococcus - classification ; Streptococcus - genetics ; Streptococcus - isolation & purification ; Streptococcus - pathogenicity ; Streptococcus infections ; Swine - microbiology]]></subject><ispartof>Molecular genetics and genomics : MGG, 2021, Vol.296 (1), p.21-31</ispartof><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020</rights><rights>Springer-Verlag GmbH Germany, part of Springer Nature 2020.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-a6b034311d36ebf5305f421937769ebb27ab5352d387641c4f83ad55d1cd1fe83</citedby><cites>FETCH-LOGICAL-c375t-a6b034311d36ebf5305f421937769ebb27ab5352d387641c4f83ad55d1cd1fe83</cites><orcidid>0000-0003-2967-8686</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/32944788$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Zongjie</creatorcontrib><creatorcontrib>Wang, Xin</creatorcontrib><creatorcontrib>Di, Di</creatorcontrib><creatorcontrib>Pan, Ruyi</creatorcontrib><creatorcontrib>Gao, Yun</creatorcontrib><creatorcontrib>Xiao, Changguang</creatorcontrib><creatorcontrib>Li, Beibei</creatorcontrib><creatorcontrib>Wei, Jianchao</creatorcontrib><creatorcontrib>Liu, Ke</creatorcontrib><creatorcontrib>Qiu, Yafeng</creatorcontrib><creatorcontrib>Ma, Zhiyong</creatorcontrib><title>Comparative analysis of the pulmonary microbiome in healthy and diseased pigs</title><title>Molecular genetics and genomics : MGG</title><addtitle>Mol Genet Genomics</addtitle><addtitle>Mol Genet Genomics</addtitle><description>The lungs possess an effective antimicrobial system and a strong ability to eliminate microorganisms in healthy organisms, and were once considered sterile. With the development of culture-independent sequencing technology, the richness and diversity of porcine lung microbiota have been gaining attention. In order to study the relationship between lung microbiota and porcine respiratory disease complex (PRDC), the lung microbiota in healthy and diseased swine bronchoalveolar lavage fluids were analyzed and compared using the Illumina MiSeq sequencing platform. The predominant microbial communities of healthy and diseased swine were similar at the phylum level, mainly composed of Proteobacteria, Firmicutes, Tenericutes, and Bacteroidetes. However, the bacterial taxonomic communities of healthy and diseased swine differed at the genus level. The higher relative abundances of
Lactococcus
,
Enterococcus
,
Staphylococcus,
and
Lactobacillus
genera in healthy swine might provide more benefits for lung health, while the enhanced richness of
Streptococcus
,
Haemophilus
,
Pasteurella,
and
Bordetella
genera in diseased swine might be closely related to pathogen invasion and the occurrence of respiratory disease. In conclusion, the observed differences in the richness and diversity of lung microbiota can provide novel insights into their relationship with PRDC. Analyses of swine lung microbiota communities might produce an effective strategy for the control and prevention of respiratory tract infections.</description><subject>Alveoli</subject><subject>Animal Genetics and Genomics</subject><subject>Animals</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Bordetella - classification</subject><subject>Bordetella - genetics</subject><subject>Bordetella - isolation & purification</subject><subject>Bordetella - pathogenicity</subject><subject>Bronchoalveolar Lavage Fluid - microbiology</subject><subject>Bronchus</subject><subject>Comparative analysis</subject><subject>DNA, Bacterial - genetics</subject><subject>Enterococcus - classification</subject><subject>Enterococcus - genetics</subject><subject>Enterococcus - isolation & purification</subject><subject>Genera</subject><subject>Haemophilus - classification</subject><subject>Haemophilus - genetics</subject><subject>Haemophilus - isolation & purification</subject><subject>Haemophilus - pathogenicity</subject><subject>High-Throughput Nucleotide Sequencing</subject><subject>Human Genetics</subject><subject>Lactobacillus - classification</subject><subject>Lactobacillus - genetics</subject><subject>Lactobacillus - isolation & purification</subject><subject>Lactococcus - classification</subject><subject>Lactococcus - genetics</subject><subject>Lactococcus - isolation & purification</subject><subject>Life Sciences</subject><subject>Lung - microbiology</subject><subject>Lung diseases</subject><subject>Microbial Genetics and Genomics</subject><subject>Microbiomes</subject><subject>Microbiota</subject><subject>Microbiota - genetics</subject><subject>Original Article</subject><subject>Pasteurella - classification</subject><subject>Pasteurella - genetics</subject><subject>Pasteurella - isolation & purification</subject><subject>Pasteurella - pathogenicity</subject><subject>Phylogeny</subject><subject>Plant Genetics and Genomics</subject><subject>Respiration</subject><subject>Respiratory diseases</subject><subject>Respiratory tract diseases</subject><subject>Respiratory Tract Infections - microbiology</subject><subject>RNA, Ribosomal, 16S - genetics</subject><subject>Staphylococcus - classification</subject><subject>Staphylococcus - genetics</subject><subject>Staphylococcus - isolation & purification</subject><subject>Streptococcus - classification</subject><subject>Streptococcus - genetics</subject><subject>Streptococcus - isolation & purification</subject><subject>Streptococcus - pathogenicity</subject><subject>Streptococcus infections</subject><subject>Swine - microbiology</subject><issn>1617-4615</issn><issn>1617-4623</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><recordid>eNp9kE1LAzEURYMotlb_gAsJuHEzmuQlk-lSil-guNF1yEwybcp8mcwI_femTq3gwlUe5Lz7uAehc0quKSHyJhDCIUsIIwmhkrFEHKApTalMeMrgcD9TMUEnIaxJpFImj9EE2JxzmWVT9LJo60573btPi3Wjq01wAbcl7lcWd0NVt432G1y7wre5a2uLXYNXVlf9ahN5g40LVgdrcOeW4RQdlboK9mz3ztD7_d3b4jF5fn14Wtw-JwVI0Sc6zQlwoNRAavNSABElZ3QOUqZzm-dM6lyAYAYymXJa8DIDbYQwtDC0tBnM0NWY2_n2Y7ChV7ULha0q3dh2CIpxHs0AMIjo5R903Q4-Ft1SGeWUkbmIFBupWDMEb0vVeVfH5ooStZWtRtkqylbfstV26WIXPeS1NfuVH7sRgBEI8atZWv97-5_YLxOHiOM</recordid><startdate>2021</startdate><enddate>2021</enddate><creator>Li, Zongjie</creator><creator>Wang, Xin</creator><creator>Di, Di</creator><creator>Pan, Ruyi</creator><creator>Gao, Yun</creator><creator>Xiao, Changguang</creator><creator>Li, Beibei</creator><creator>Wei, Jianchao</creator><creator>Liu, Ke</creator><creator>Qiu, Yafeng</creator><creator>Ma, Zhiyong</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7SS</scope><scope>7TK</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>RC3</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-2967-8686</orcidid></search><sort><creationdate>2021</creationdate><title>Comparative analysis of the pulmonary microbiome in healthy and diseased pigs</title><author>Li, Zongjie ; Wang, Xin ; Di, Di ; Pan, Ruyi ; Gao, Yun ; Xiao, Changguang ; Li, Beibei ; Wei, Jianchao ; Liu, Ke ; Qiu, Yafeng ; Ma, Zhiyong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-a6b034311d36ebf5305f421937769ebb27ab5352d387641c4f83ad55d1cd1fe83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Alveoli</topic><topic>Animal Genetics and Genomics</topic><topic>Animals</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Bordetella - classification</topic><topic>Bordetella - genetics</topic><topic>Bordetella - isolation & purification</topic><topic>Bordetella - pathogenicity</topic><topic>Bronchoalveolar Lavage Fluid - microbiology</topic><topic>Bronchus</topic><topic>Comparative analysis</topic><topic>DNA, Bacterial - genetics</topic><topic>Enterococcus - classification</topic><topic>Enterococcus - genetics</topic><topic>Enterococcus - isolation & purification</topic><topic>Genera</topic><topic>Haemophilus - classification</topic><topic>Haemophilus - genetics</topic><topic>Haemophilus - isolation & purification</topic><topic>Haemophilus - pathogenicity</topic><topic>High-Throughput Nucleotide Sequencing</topic><topic>Human Genetics</topic><topic>Lactobacillus - classification</topic><topic>Lactobacillus - genetics</topic><topic>Lactobacillus - isolation & purification</topic><topic>Lactococcus - classification</topic><topic>Lactococcus - genetics</topic><topic>Lactococcus - isolation & purification</topic><topic>Life Sciences</topic><topic>Lung - microbiology</topic><topic>Lung diseases</topic><topic>Microbial Genetics and Genomics</topic><topic>Microbiomes</topic><topic>Microbiota</topic><topic>Microbiota - genetics</topic><topic>Original Article</topic><topic>Pasteurella - classification</topic><topic>Pasteurella - genetics</topic><topic>Pasteurella - isolation & purification</topic><topic>Pasteurella - pathogenicity</topic><topic>Phylogeny</topic><topic>Plant Genetics and Genomics</topic><topic>Respiration</topic><topic>Respiratory diseases</topic><topic>Respiratory tract diseases</topic><topic>Respiratory Tract Infections - microbiology</topic><topic>RNA, Ribosomal, 16S - genetics</topic><topic>Staphylococcus - classification</topic><topic>Staphylococcus - genetics</topic><topic>Staphylococcus - isolation & purification</topic><topic>Streptococcus - classification</topic><topic>Streptococcus - genetics</topic><topic>Streptococcus - isolation & purification</topic><topic>Streptococcus - pathogenicity</topic><topic>Streptococcus infections</topic><topic>Swine - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Zongjie</creatorcontrib><creatorcontrib>Wang, Xin</creatorcontrib><creatorcontrib>Di, Di</creatorcontrib><creatorcontrib>Pan, Ruyi</creatorcontrib><creatorcontrib>Gao, Yun</creatorcontrib><creatorcontrib>Xiao, Changguang</creatorcontrib><creatorcontrib>Li, Beibei</creatorcontrib><creatorcontrib>Wei, Jianchao</creatorcontrib><creatorcontrib>Liu, Ke</creatorcontrib><creatorcontrib>Qiu, Yafeng</creatorcontrib><creatorcontrib>Ma, Zhiyong</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>ProQuest_Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Databases</collection><collection>ProQuest Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest Biological Science Journals</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Molecular genetics and genomics : MGG</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Zongjie</au><au>Wang, Xin</au><au>Di, Di</au><au>Pan, Ruyi</au><au>Gao, Yun</au><au>Xiao, Changguang</au><au>Li, Beibei</au><au>Wei, Jianchao</au><au>Liu, Ke</au><au>Qiu, Yafeng</au><au>Ma, Zhiyong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative analysis of the pulmonary microbiome in healthy and diseased pigs</atitle><jtitle>Molecular genetics and genomics : MGG</jtitle><stitle>Mol Genet Genomics</stitle><addtitle>Mol Genet Genomics</addtitle><date>2021</date><risdate>2021</risdate><volume>296</volume><issue>1</issue><spage>21</spage><epage>31</epage><pages>21-31</pages><issn>1617-4615</issn><eissn>1617-4623</eissn><abstract>The lungs possess an effective antimicrobial system and a strong ability to eliminate microorganisms in healthy organisms, and were once considered sterile. With the development of culture-independent sequencing technology, the richness and diversity of porcine lung microbiota have been gaining attention. In order to study the relationship between lung microbiota and porcine respiratory disease complex (PRDC), the lung microbiota in healthy and diseased swine bronchoalveolar lavage fluids were analyzed and compared using the Illumina MiSeq sequencing platform. The predominant microbial communities of healthy and diseased swine were similar at the phylum level, mainly composed of Proteobacteria, Firmicutes, Tenericutes, and Bacteroidetes. However, the bacterial taxonomic communities of healthy and diseased swine differed at the genus level. The higher relative abundances of
Lactococcus
,
Enterococcus
,
Staphylococcus,
and
Lactobacillus
genera in healthy swine might provide more benefits for lung health, while the enhanced richness of
Streptococcus
,
Haemophilus
,
Pasteurella,
and
Bordetella
genera in diseased swine might be closely related to pathogen invasion and the occurrence of respiratory disease. In conclusion, the observed differences in the richness and diversity of lung microbiota can provide novel insights into their relationship with PRDC. Analyses of swine lung microbiota communities might produce an effective strategy for the control and prevention of respiratory tract infections.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>32944788</pmid><doi>10.1007/s00438-020-01722-5</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0003-2967-8686</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1617-4615 |
| ispartof | Molecular genetics and genomics : MGG, 2021, Vol.296 (1), p.21-31 |
| issn | 1617-4615 1617-4623 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2444383323 |
| source | Springer Link |
| subjects | Alveoli Animal Genetics and Genomics Animals Biochemistry Biomedical and Life Sciences Bordetella - classification Bordetella - genetics Bordetella - isolation & purification Bordetella - pathogenicity Bronchoalveolar Lavage Fluid - microbiology Bronchus Comparative analysis DNA, Bacterial - genetics Enterococcus - classification Enterococcus - genetics Enterococcus - isolation & purification Genera Haemophilus - classification Haemophilus - genetics Haemophilus - isolation & purification Haemophilus - pathogenicity High-Throughput Nucleotide Sequencing Human Genetics Lactobacillus - classification Lactobacillus - genetics Lactobacillus - isolation & purification Lactococcus - classification Lactococcus - genetics Lactococcus - isolation & purification Life Sciences Lung - microbiology Lung diseases Microbial Genetics and Genomics Microbiomes Microbiota Microbiota - genetics Original Article Pasteurella - classification Pasteurella - genetics Pasteurella - isolation & purification Pasteurella - pathogenicity Phylogeny Plant Genetics and Genomics Respiration Respiratory diseases Respiratory tract diseases Respiratory Tract Infections - microbiology RNA, Ribosomal, 16S - genetics Staphylococcus - classification Staphylococcus - genetics Staphylococcus - isolation & purification Streptococcus - classification Streptococcus - genetics Streptococcus - isolation & purification Streptococcus - pathogenicity Streptococcus infections Swine - microbiology |
| title | Comparative analysis of the pulmonary microbiome in healthy and diseased pigs |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T06%3A30%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Comparative%20analysis%20of%20the%20pulmonary%20microbiome%20in%20healthy%20and%20diseased%20pigs&rft.jtitle=Molecular%20genetics%20and%20genomics%20:%20MGG&rft.au=Li,%20Zongjie&rft.date=2021&rft.volume=296&rft.issue=1&rft.spage=21&rft.epage=31&rft.pages=21-31&rft.issn=1617-4615&rft.eissn=1617-4623&rft_id=info:doi/10.1007/s00438-020-01722-5&rft_dat=%3Cproquest_cross%3E2481412095%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c375t-a6b034311d36ebf5305f421937769ebb27ab5352d387641c4f83ad55d1cd1fe83%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2481412095&rft_id=info:pmid/32944788&rfr_iscdi=true |