Modern trends in diuretics development

Diuretics are the first-line therapy for widespread cardiovascular and non-cardiovascular diseases. Traditional diuretics are commonly prescribed for treatment in patients with hypertension, edema and heart failure, as well as with a number of kidney problems. They are diseases with high mortality,...

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Bibliographic Details
Published in:European journal of medicinal chemistry 2020-12, Vol.208, p.112855, Article 112855
Main Authors: Titko, Tetiana, Perekhoda, Lina, Drapak, Iryna, Tsapko, Yevgen
Format: Article
Language:English
Subjects:
Aquaporin (AQP)
Diuretics
ROMK
SGLT2 inhibitors (gliflozins)
Small molecular drugs
Urea transporter (UT)
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