Biosynthesis of AgNPs onto the urea-based periodic mesoporous organosilica (AgxNPs/Ur-PMO) for antibacterial and cell viability assay

[Display omitted] Nano-size silver particles were stabilized on the inner surfaces of urea based periodic mesoporous organosilica (Ur-PMO). Aqueous extract of Euphorbia leaves as a sustainable and green reducing agent was applied for Ag-nanoparticles growth into the Ur-PMO channels. Physical and che...

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Bibliographic Details
Published in:Journal of colloid and interface science 2021-03, Vol.585, p.676-683
Main Authors: Hasanzadeh, Amir, Gholipour, Behnam, Rostamnia, Sadegh, Eftekhari, Aziz, Tanomand, Asghar, Valizadeh. K, Ali, Khaksar, Samad, Khalilov, Rovshan
Format: Article
Language:English
Subjects:
AgNPs
Antibacterial activity
Cell viability assay
Periodic mesoporous organosilica (PMO)
Urea-based PMO (Ur-PMO)
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Summary:[Display omitted] Nano-size silver particles were stabilized on the inner surfaces of urea based periodic mesoporous organosilica (Ur-PMO). Aqueous extract of Euphorbia leaves as a sustainable and green reducing agent was applied for Ag-nanoparticles growth into the Ur-PMO channels. Physical and chemical properties of organosilica materials synthesized using various techniques such as FT-IR, small-angle XRD, PXRD, FESEM, TEM, SEM-EDX and atomic absorption spectrometry (AAS) were examined. Finally, the AgNPs/Ur-PMO were investigated on cell viability assay. An in vitro cytotoxicity test using MMT assay displayed that the designed material has good biocompatibility and could be a promising candidate for biomedical applications. The results also showed that the AgNPs/Ur-PMO compounds (especially, PMO; 1.27% AgNPs) had relatively good antibacterial and antibiofilm effects. It seems that the use of these compounds in hospital environments can reduce nosocomial infections as well as reduce antibiotic-resistant bacteria.
ISSN:0021-9797
1095-7103
DOI:10.1016/j.jcis.2020.10.047