The impact of pre‐eclampsia definitions on the identification of adverse outcome risk in hypertensive pregnancy – analyses from the CHIPS trial (Control of Hypertension in Pregnancy Study)

Objective To examine the association between pre‐eclampsia definition and pregnancy outcome. Design Secondary analysis of Control of Hypertension in Pregnancy Study (CHIPS) trial data. Setting International multicentre randomised controlled trial (RCT). Population In all, 987 women with non‐severe n...

Full description

Saved in:
Bibliographic Details
Published in:BJOG : an international journal of obstetrics and gynaecology 2021-07, Vol.128 (8), p.1373-1382
Main Authors: Magee, LA, Singer, J, Lee, T, Rey, E, Asztalos, E, Hutton, E, Helewa, M, Logan, AG, Ganzevoort, W, Welch, R, Thornton, JG, Woo Kinshella, ML, Green, M, Tsigas, E, Dadelszen, P
Format: Article
Language:English
Subjects:
Birth weight
Blood pressure
Definition
Eclampsia
Hypertension
maternal outcome
Neonates
perinatal outcome
Preeclampsia
Pregnancy
pre‐eclampsia
Proteinuria
severe hypertension
Womens health
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective To examine the association between pre‐eclampsia definition and pregnancy outcome. Design Secondary analysis of Control of Hypertension in Pregnancy Study (CHIPS) trial data. Setting International multicentre randomised controlled trial (RCT). Population In all, 987 women with non‐severe non‐proteinuric pregnancy hypertension. Methods We evaluated the association between pre‐eclampsia definitions and adverse pregnancy outcomes, stratified by hypertension type and blood pressure control. Main outcome measures Main CHIPS trial outcomes: primary (perinatal loss or high‐level neonatal care for >48 hours), secondary (serious maternal complications), birthweight
ISSN:1470-0328
1471-0528
DOI:10.1111/1471-0528.16602