Impact of Obesity and Visceral Fat on Mortality in Hematopoietic Stem Cell Transplantation

Rationale: Many studies have shown the importance of body composition parameters, muscle, and fat mass, evaluated by several methods in hematopoietic stem cell transplantation (HSCT) outcomes. Ultrasound (US) is an efficient and low‐cost method to evaluate body composition, even though there have no...

Full description

Saved in:
Bibliographic Details
Published in:JPEN. Journal of parenteral and enteral nutrition 2021-09, Vol.45 (7), p.1597-1603
Main Authors: Pereira, Andrea Z, Almeida‐Pitito, Bianca, Eugenio, Gisele Cristine, Ruscitto do Prado, Rogério, Silva, Cinthya Correa, Hamerschlak, Nelson
Format: Article
Language:English
Subjects:
fat mass
hematopoietic cell transplant
lean mass
muscle mass
nutrition
ultrasound
visceral fat
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Rationale: Many studies have shown the importance of body composition parameters, muscle, and fat mass, evaluated by several methods in hematopoietic stem cell transplantation (HSCT) outcomes. Ultrasound (US) is an efficient and low‐cost method to evaluate body composition, even though there have not been many studies in HSCT. Objectives: Our goal was to investigate the muscle, visceral fat (VF), and echogenicity before HSCT and after engraftment, evaluated by US and its association with outcomes. Methods: All adult patients with hematological malignances admitted for HSCT autologous and allogeneic were eligible to enter this prospective study. Their thigh muscle thickness, VF, and echogenicity were evaluated by US on the first day of hospitalization (baseline) and after engraftment (15–25 days post‐HSCT). Results: We evaluated 50 patients; 42% were male and 58% had undergone allogeneic HSCT. Most patients were
ISSN:0148-6071
1941-2444
DOI:10.1002/jpen.2048