Assessing vaccination reactions in pediatric patients with maculopapular cutaneous mastocytosis

Immunization compliance in the United States is declining, in part due to misinformation and fear surrounding adverse vaccination reactions. Recently, there have been data published in the allergy and immunology literature to show that there may be a relationship between routine vaccinations and ind...

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Bibliographic Details
Published in:Pediatric dermatology 2021-03, Vol.38 (2), p.502-503
Main Authors: Johansen, Maija L., Lawley, Leslie P.
Format: Article
Language:English
Subjects:
Allergies
Cell activation
Child
Dermatology
Humans
Hypersensitivity
Immunization
immunizations
maculopapular cutaneous mastocytosis
Mastocytosis
Mastocytosis, Cutaneous - epidemiology
Pediatrics
Skin cancer
Urticaria Pigmentosa
Vaccination
vaccination reactions
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Summary:Immunization compliance in the United States is declining, in part due to misinformation and fear surrounding adverse vaccination reactions. Recently, there have been data published in the allergy and immunology literature to show that there may be a relationship between routine vaccinations and induction of symptoms in cutaneous mastocytosis patients; however, this has not yet been explored in the dermatology literature. We sought to uncover the prevalence of vaccine reactions due to mast cell activation within our cohort of maculopapular cutaneous mastocytosis (MPCM) patients in order to contribute to ensuring administration safety, managing familial expectations, and encouraging continued adherence. Our results indicate that while incidence of reaction rates may be higher than the national average, they are mild and families should be counseled to follow recommended immunization schedule guidelines.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.14492