Stereotactic gamma knife radiosurgery for orbital cavernous hemangioma: clinical outcome and visual function protection

Purpose Although rare, orbital cavernous hemangioma (OCH) is the most common benign orbital neoplasm in adults and may cause vision disturbance or loss due to optic nerve compression. The conventional treatment is surgical excision, which carries a risk of intraoperative nerve damage, whereas gamma...

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Bibliographic Details
Published in:Journal of neuro-oncology 2021-03, Vol.152 (1), p.183-193
Main Authors: Chen, Hsien-Chung, Hu, Chaur-Jong, Pan, David Hung-Chi
Format: Article
Language:English
Subjects:
Acuity
Cancer
Clinical outcomes
Clinical Study
Compression
Eye diseases
Hemangioma
Magnetic resonance imaging
Medicine
Medicine & Public Health
Neurology
Oncology
Optic nerve
Patients
Radiosurgery
Vision
Visual perception
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Summary:Purpose Although rare, orbital cavernous hemangioma (OCH) is the most common benign orbital neoplasm in adults and may cause vision disturbance or loss due to optic nerve compression. The conventional treatment is surgical excision, which carries a risk of intraoperative nerve damage, whereas gamma knife radiosurgery (GKRS) can be a safe and effective alternative. Herein, we report the results of four patients with OCH treated with GKRS, and describe the method of treatment including the optic nerve protection. Methods This retrospective study included four consecutive patients (three women, one man; mean age: 50 ± 14.7 years) with OCH treated with single-session GKRS between 2014 and 2020. Three patients had decreased visual acuity. During GKRS, the prescription dose delivered to the tumor margin was 12 Gy at the 55–58% isodose line. The dose to the optic nerve margin was
ISSN:0167-594X
1573-7373
DOI:10.1007/s11060-020-03692-5