The emerging role of 3D-printing in ion mobility spectrometry and mass spectrometry

3D-printing is revolutionizing the rapid prototyping in analytical chemistry. In the last few years, we observed the development of 3D-printed components for ion studies, such as ion sources, ion transfer and ion mobility spectrometry (IMS) devices. Often, 3D-printed gadgets add functions to existin...

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Bibliographic Details
Published in:Analytical methods 2021-02, Vol.13 (7), p.852-861
Main Authors: Guillén-Alonso, Héctor, Rosas-Román, Ignacio, Winkler, Robert
Format: Article
Language:English
Subjects:
Adapters
Analytical chemistry
Coupling (molecular)
Ion sources
Ionic mobility
Ionization
Ions
Mass spectrometry
Mass spectroscopy
Mobility
Printing
Rapid prototyping
Sample preparation
Scientific imaging
Spectroscopy
Three dimensional printing
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Summary:3D-printing is revolutionizing the rapid prototyping in analytical chemistry. In the last few years, we observed the development of 3D-printed components for ion studies, such as ion sources, ion transfer and ion mobility spectrometry (IMS) devices. Often, 3D-printed gadgets add functions to existing mass spectrometry (MS) systems. Custom adapters improve the sensibility for coupling with ambient ionization and upstream chromatography methods, and sample preparation units optimize the following MS analyses. Besides, 3D-printer parts are suitable for constructing custom analytical robots and mass imaging systems. Some of those assemblies implement new concepts and are commercially not available. An essential aspect of using 3D-printing is the fast turnover of design improvements, which is motivated by permissive licenses. The easy reproducibility and exchange of ideas lead to a community-driven development, which is accompanied by economic advantages for public research and education. 3D-printing enables the rapid prototyping of ion mobility (IMS) and mass spectrometry (MS) gadgets. The RepRap components are suitable for building cost-efficient robots and MS imaging systems. In this review, we present current trends.
ISSN:1759-9660
1759-9679
DOI:10.1039/d0ay02290j