Useful hearing preservation is improved in vestibular schwannoma patients who undergo stereotactic radiosurgery before further hearing deterioration ensues

Introduction The present study evaluates whether hearing deterioration during observation reduces serviceable hearing preservation rates after stereotactic radiosurgery (SRS) in vestibular schwannoma (VS) patients with useful hearing. Methods We retrospectively analyzed 1447 VS patients who underwen...

Full description

Saved in:
Bibliographic Details
Published in:Journal of neuro-oncology 2021-05, Vol.152 (3), p.559-566
Main Authors: Ogino, Akiyoshi, Long, Hao, Johnson, Stephen, Faramand, Andrew, Niranjan, Ajay, Flickinger, John C., Lunsford, L. Dade, Kano, Hideyuki
Format: Article
Language:English
Subjects:
Clinical Study
Diagnosis
Hearing
Hearing Loss - etiology
Humans
Medicine
Medicine & Public Health
Middle Aged
Multivariate analysis
Neurology
Neuroma, Acoustic - complications
Neuroma, Acoustic - diagnostic imaging
Neuroma, Acoustic - radiotherapy
Niacinamide
Oncology
Preservation
Radiosurgery
Radiosurgery - adverse effects
Retrospective Studies
Schwann cells
Surgery
Treatment Outcome
Vestibular system
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction The present study evaluates whether hearing deterioration during observation reduces serviceable hearing preservation rates after stereotactic radiosurgery (SRS) in vestibular schwannoma (VS) patients with useful hearing. Methods We retrospectively analyzed 1447 VS patients who underwent SRS between 1992 and 2017. We identified 100 VS patients who had Grade I Gardner- Robertson (GR) hearing at initial diagnosis but were observed without surgery or SRS. We compared hearing after SRS in 67 patients who retained GR Grade I hearing from initial diagnosis to SRS (the hearing maintenance or HM group) to 33 patients whose hearing worsened from GR grade I to grade II (the hearing deterioration or HD group). We also investigated whether a decline in pure tone average (PTA) or speech discrimination score (SDS) before SRS affected hearing preservation after SRS. Results The serviceable hearing (GR I and II) preservation in HM patients was 80%s, 63%, and 51% at 3, 5, and 10 years, respectively. The serviceable hearing preservation in HD patients was 40%, 33%, and 20% at 3, 5, and 10 years, respectively. In multivariate analysis, younger age (
ISSN:0167-594X
1573-7373
DOI:10.1007/s11060-021-03726-6