Leaflet Dimensions as a Guide to Remodeling Annuloplasty During Aortic Valve Repair

• Published in: Innovations (Philadelphia, Pa.) Pa.), 2021-05, Vol.16 (3), p.267-272
• Main Authors: Jasinski, Marek J., Rankin, J. Scott, Mazzitelli, Domenico, Fischlein, Theodor, Choi, Yeong-Hoon, Wei, Lawrence M., Deja, Marek A., Badhwar, Vinay
• Format: Article
• Language: English
• ISSN: 1556-9845; 1559-0879
• DOI: 10.1177/1556984521997422

Objective In chronic aortic insufficiency (AI), the method and degree of annular downsizing required to achieve durable coaptation in aortic valve repair (AVr) remains poorly defined. This study evaluated the relationship between leaflet size and annular diameter to predict adequate annular sizing in remodeling AVr. Methods Under regulatory supervision, 74 patients with chronic tri-leaflet AI underwent AVr using ring annuloplasty and leaflet reconstruction. Fifty-four (73%) had ascending aortic (n = 25) and/or root (n = 29) aneurysms, and aortic grafts were sized 5 to 7 mm larger than the rings. Intraoperatively, leaflet free-edge length (FEL) was measured with special ball sizers positioned in the coronary sinus, and “normal” annular diameter was predicted from the validated formula: Required “normal” diameter = FEL/1.5. “Normal” annular diameters predicted from FEL were compared with pathologic diameters measured intraoperatively with Hegar dilators, and both were correlated with gender, age, and BSA. Results Average age was 62.1 ± 13.3 years (mean ± SD), 73% (54/74) were male, and 96% (71/74) had moderate-to-severe AI. All patients had annular dilatation, with a pathologic diameter 26.6 ± 2.3 mm before repair, and a predicted “normal” diameter of 21.7 ± 1.7 mm (P < 0.001). Both predicted and pathologic annular diameters were larger in men (P < 0.001), but no relationship existed with age. BSA correlated with both predicted and pathologic diameters, although variability was large. Conclusions Based on a simple validated method to predict “normal” annular diameter, all patients with chronic AI have some degree of annular dilatation. This finding implies that most AVr should include annuloplasty, with adequate and precise annular reduction based on leaflet size.