Vitamin K antagonists did not increase the risk of myelodysplastic syndrome in a large-scale cohort study

It has recently been reported that vitamin K antagonists (VKAs) impair the bone marrow microenvironment and may predispose to myelodysplastic syndrome (MDS). In a study of the French national health care database, Neumann et al examined data on this issue for more than 120 000 individuals on oral an...

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Bibliographic Details
Published in:Blood 2021-08, Vol.138 (5), p.417-420
Main Authors: Neumann, Anke, Jabagi, Marie-Joelle, Zureik, Mahmoud
Format: Article
Language:English
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Summary:It has recently been reported that vitamin K antagonists (VKAs) impair the bone marrow microenvironment and may predispose to myelodysplastic syndrome (MDS). In a study of the French national health care database, Neumann et al examined data on this issue for more than 120 000 individuals on oral anticoagulation for atrial fibrillation, confirming that there is no increase in MDS in patients treated with VKAs in comparison with those treated with direct oral anticoagulants.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.2021010848