Malignancies requiring temporal bone resection: An Australian single‐institution experience

Background Malignancies in and around the temporal bone are aggressive and difficult to manage. In Queensland (Australia), where skin cancer rates are exceedingly high, tumours extending to the temporal bone from surrounding structures occur more commonly than primary cancers. Yet, a paucity of evid...

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Bibliographic Details
Published in:ANZ journal of surgery 2021-07, Vol.91 (7-8), p.1462-1471
Main Authors: Schachtel, Michael J. C., Gandhi, Mitesh, Bowman, James J., Erian, Christopher, Porceddu, Sandro V., Panizza, Benedict J.
Format: Article
Language:English
Subjects:
Bone cancer
Cancer
ear neoplasms
Epidemiology
Head & neck cancer
Malignancy
Melanoma
Oral cancer
parotid neoplasms
Patients
Skin cancer
skin neoplasms
skull base neoplasms
Squamous cell carcinoma
Survival
Temporal bone
Tumors
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Summary:Background Malignancies in and around the temporal bone are aggressive and difficult to manage. In Queensland (Australia), where skin cancer rates are exceedingly high, tumours extending to the temporal bone from surrounding structures occur more commonly than primary cancers. Yet, a paucity of evidence exists as to their management and outcomes. This study aimed to review an Australian centre's experience of managing temporal and peritemporal bone malignancies, reporting on patient and tumour characteristics, treatment, and survival outcomes. Methods Retrospective analysis of patients with primary temporal bone cancer and cancers extending to the temporal bone managed by the Queensland Skull Base Unit (Princess Alexandra Hospital) between 2000 and 2019. Results A total of 222 patients were identified, of which 203 (91.4%) had cutaneous primaries, with 167 (75.2%) being squamous cell carcinoma (SCC). 73.9% presented with locoregionally recurrent or residual disease. Secondary tumours (92.8%) were 12 times more frequent than primary malignancies (7.2%), with the preauricular subsite the most common (45.5%). In the 201 patients (90.5%) who underwent curative intent surgery, 5‐year overall survival, disease‐free survival (DFS), and disease‐specific survival was 46.6%, 52.2%, and 65.9%, respectively. The preauricular subsite (p = 0.004), melanoma (vs. SCC, p = 0.027), involved margins (p 
ISSN:1445-1433
1445-2197
DOI:10.1111/ans.16931