No evidence of the clinical utility of single-item breakpoint to inform on tobacco demand in persons with substance use disorders

Rationale Behavioral economics has shown that single-item demand indicators are promising for capturing crucial aspects of nicotine reinforcement. It is suggested that brief breakpoint measures perform comparably to full-length demand indices in characterizing nicotine dependence; however, there hav...

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Bibliographic Details
Published in:Psychopharmacology 2021-09, Vol.238 (9), p.2525-2533
Main Authors: González-Roz, Alba, Secades-Villa, Roberto, Aonso-Diego, Gema, Weidberg, Sara, Fernández-Hermida, José R.
Format: Article
Language:English
Subjects:
Addictions
Analysis
Behavioral economics
Biomedical and Life Sciences
Biomedicine
Drug dependence
Drug use
Female
Humans
Male
Neurosciences
Nicotine
Original Investigation
Pharmacology/Toxicology
Psychiatry
Smokers
Smoking
Substance use disorder
Substance-Related Disorders
Tobacco
Tobacco habit
Tobacco Products
Tobacco Use Disorder
Validity
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Summary:Rationale Behavioral economics has shown that single-item demand indicators are promising for capturing crucial aspects of nicotine reinforcement. It is suggested that brief breakpoint measures perform comparably to full-length demand indices in characterizing nicotine dependence; however, there have been no thorough assessments of their validity in clinical settings. Objectives This study aimed to assess the validity and accuracy of a single-item breakpoint in informing on tobacco demand. Methods The sample consisted of 88 treatment-seeking smokers (% males = 70.5%) enrolled in substance use treatment. Participants provided data on smoking characteristics and completed the Fagerström Test for Nicotine Dependence, a single-item breakpoint measure and a 14-item cigarette purchase task (CPT). Hierarchical regressions were performed to compare the predictive capability of a single-item breakpoint and full-length tobacco demand indicators in determining nicotine addiction severity. Results The single-item breakpoint was significantly correlated with all indices stemmed from the CPT and both latent factors (all r values = .250–.368). Neither the brief breakpoint nor the full-length breakpoint significantly predicted nicotine dependence. After controlling for sex and smoking variables, factor 2 [ β  = .565, p  
ISSN:0033-3158
1432-2072
1432-2072
DOI:10.1007/s00213-021-05875-y