National Quality Evaluation of Medication Use for Pediatric Otitis Media With Effusion

• Published in: Ear, nose, & throat journal nose, & throat journal, 2023-11, Vol.102 (11), p.NP567-NP573
• Main Authors: Chen, Yu-Lu, Fang, Te-Yung, Wang, Pa-Chun, Chen, Ya-Hui, Wang, Ting-Chuan, Huang, Wan-Tsui
• Format: Article
• Language: English
• Subjects: Antibiotics; Clinical medicine; Clinical practice guidelines; Drug use; Ear diseases; Histamine; Pediatrics; Steroids
• ISSN: 0145-5613; 1942-7522
• DOI: 10.1177/01455613211020531

Objectives: Otitis media with effusion (OME) is characterized by the presence of fluid in the middle ear without the presentation of signs or symptoms of acute ear infection. The point prevalence of OME reaches as high as 60% in children younger than 2 years of age. We used the National Health Insurance Research Database (NHIRD) to investigate the use of medication in children with OME before receiving ventilation tube insertion (VTI). Methods: Data of pediatric patients (age ≤ 12 years) who had OME and received VTI from January 1, 2011, to December 30, 2012, were retrieved from the Taiwan NHIRD. We surveyed the use of 4 medications to understand whether health care providers achieved the standards of medication use recommended by clinical practice guidelines. Results: This study examines the factors affecting the use of medication for pediatric OME. Overall, according to the study’s operational definitions, the use of systemic antibiotics was most common (59.9%), followed by systemic antihistamines (23.4%), systemic steroids (8.8%), and intranasal steroids (9.6%). Systemic antibiotics use was associated with 12 factors. Ten of the 12 factors increase the use of systemic antibiotics, including namely age (age > 2 years), comorbidities, teaching hospital, and community hospital. In contrast, namely catastrophic illness and watchful waiting are the 2 factors that decrease systemic antibiotics use. For the use of systemic antihistamines, systemic steroids, and intranasal steroids were related to 6, 5, and 2 factors, respectively. Conclusions: The rate of drug use differs from the rate of use recommended by commonly used clinical practice guidelines. We found that the higher the number of factors that influenced the patients’ drug use, the higher the rate of drug use. According to these results, drafting a treatment guideline for OME patients in accordance with current clinical practices in Taiwan is highly recommended.