Risk of death due to other causes is lower among octogenarians with non-small cell lung cancer after wedge resection than lobectomy/segmentectomy

• Published in: Japanese journal of clinical oncology 2021-10, Vol.51 (10), p.1561-1569
• Main Authors: Mimae, Takahiro, Miyata, Yoshihiro, Yoshimura, Kenichi, Tsutani, Yasuhiro, Imai, Kentaro, Ito, Hiroyuki, Nakayama, Haruhiko, Ikeda, Norihiko, Okada, Morihito
• Format: Article
• Language: English
• ISSN: 1465-3621; 1465-3621
• DOI: 10.1093/jjco/hyab122

Abstract Objective We aimed to determine the influences of surgical procedures on the postoperative death of octogenarians with clinical Stage IA non-small cell lung cancer excluding cT1mi. Methods We compared overall survival and the cumulative incidence of death due to all and other causes among 1 130 279, and 191 consecutive patients aged ≤79 and ≥80 years after lobectomy, segmentectomy and wedge resection at three institutions. Death due to other causes was defined as death due to any cause except non-small cell lung cancer. Results The median followup was 53 months. The 5-year overall survival rates for patients aged ≥ 80 and ≤ 79 years after lobectomy, segmentectomy and wedge resection were respectively, 78.0% (95% confidence interval, 63.8%–87.2%) versus 91.2% (95% confidence interval, 89.0%–92.9%), 68.1% (95% confidence interval, 45.2%–83.1%) versus 90.0% (95% confidence interval, 84.6%–93.5%), and 62.7% (95% confidence interval, 44.0–76.7%) versus 84.4% (95% confidence interval, 76.3%–89.9%) (P