Demographic, cardiological, microbiologic, and dental profiles of Brazilian patients who developed oral bacteria–related endocarditis

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology oral medicine, oral pathology and oral radiology, 2021-10, Vol.132 (4), p.418-425
• Main Authors: Montano, Tânia Cristina Pedroso, Wanderley, Marcelo Ivander Andrade, Sampaio, Roney Orismar, Alves, Carolina Guimarães Bonfim, Neves, Itamara Lúcia Itagiba, Lopes, Marcio Ajudarte, Tarasoutchi, Flavio, Strabelli, Tânia Mara Varejão, Neves, Ricardo Simões, Grinberg, Max, Santos-Silva, Alan Roger, Siciliano, Rinaldo Focaccia
• Format: Article
• Language: English
• Subjects: Dentistry
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2021.07.007

Infective endocarditis (IE) may cause devastating complications with high morbidity and mortality rates. The aim of the present study was to study the demographic, cardiological, microbiologic, and dental profiles of patients with oral bacteria–related IE. We present a retrospective study of patients with oral bacteria–related IE treated at Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de Sao Paulo, Brazil, between January 2009 and December 2019. Of the 100 patients included, 70% were male with a mean age of 45.4 years at diagnosis. The most affected sites were aortic and mitral valves, 60% in prosthetic heart valves, 34% in native valves, and 3% in pacemakers. The most common cause of valvular disease was rheumatic cardiopathy (51.9%), and the most frequent complications were valvular and perivalvular damage (26%). Streptococcus viridans was the most common species (96%), dental caries were present in 57% of the patients, 78% had tooth loss, 45% had apical periodontitis, and 77% were at high/moderate risk for periodontal disease. Oral bacteria–related IE among Brazilians was predominant in the prosthetic heart valves of young male adults previously affected by rheumatic cardiopathy. Streptococcus viridans was the main cause of IE, which was linked to patients with a poor oral health status.