Simultaneous determination of mitotane, its metabolite, and five steroid hormones in urine samples by capillary electrophoresis using β-CD2 SDS1 complexes as hydrophobic compounds solubilizers

Mitotane is a cytotoxic drug used in the treatment of inoperable adrenocortical carcinoma, it inhibits steroidogenesis as well, and therefore monitoring the level of steroid hormones in patients treated with mitotane is a crucial point of therapy. Hence, we have developed a simple, fast, and efficie...

Full description

Saved in:
Bibliographic Details
Published in:Electrophoresis 2022-05, Vol.43 (9-10), p.990
Main Authors: Pieckowski, Michał, Kowalski, Piotr, Olędzka, Ilona, Miękus-Purwin, Natalia, Plenis, Alina, Roszkowska, Anna, Bączek, Tomasz
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!