Relationship of serum 25- hydroxy vitamin D and systemic lupus erythematosus

To investigate the application value of serum 25-hydroxy vitamin D [25(OH)D] in systemic lupus erythematosus (SLE). Data of 158 patients with SLE in Department of Rheumatology and Immunology in the People's Hospital of Xinjiang Uygur Autonomous Region from July 2016 to July 2019. All the SLE pa...

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Bibliographic Details
Published in:Beijing da xue xue bao. Journal of Peking University. Yi xue ban 2021-10, Vol.53 (5), p.938-941
Main Authors: Zou, J M, Wu, L J, Luo, C N, Shi, Y M, Wu, X
Format: Article
Language:Chinese
Subjects:
Antibodies, Antinuclear
Humans
Lupus Erythematosus, Systemic
Lupus Nephritis
Vitamin D - analogs & derivatives
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Summary:To investigate the application value of serum 25-hydroxy vitamin D [25(OH)D] in systemic lupus erythematosus (SLE). Data of 158 patients with SLE in Department of Rheumatology and Immunology in the People's Hospital of Xinjiang Uygur Autonomous Region from July 2016 to July 2019. All the SLE patients were divided into two groups by SLE scores of the disease activity index (SLEADI): 59 cases of active group (SLEADI > 4), 99 cases of non-active group (SLEDAI ≤4). Fifty healthy people were selected as healthy control group. The patients' general information and their laboratory data including serum 25(OH)D levels were collected. Statistical methods used were -test, Spearman's correalation analysis and Logistic regression analysis. (1) A total of 208 cases were included in this study. The level of 25(OH)D in SLE group [10.4(5.6, 15.8) μg/L] was significantly lower than that in healthy control group [25.5(22.8, 32.3) μg/L, < 0.01]. 25(OH)D level in active SLE patients [6.2(3.7, 13.8) μg/L] was significantly lower
ISSN:1671-167X