Hysteroscopic management of retained products of conception: A systematic review

• Published in: Australian & New Zealand journal of obstetrics & gynaecology 2022-02, Vol.62 (1), p.22-32
• Main Authors: Taylor, Cassandra, Ellett, Lenore, Hiscock, Richard, Mooney, Samantha
• Format: Article
• Language: English
• Subjects: dilation and curettage; Female; Humans; hysteroscopy; Hysteroscopy - adverse effects; Hysteroscopy - methods; intra uterine adhesions; Pregnancy; pregnancy complications; products of conception; Prospective Studies; Retrospective Studies; Tissue Adhesions; Uterine Diseases - surgery
• ISSN: 0004-8666; 1479-828X
• DOI: 10.1111/ajo.13455

Background The management of retained products of conception (RPOC) is not well standardised due to a lack of evidence‐based guidelines. Hysteroscopic resection has been proven to be safe and is hypothesised to have lower risk than dilation and curettage, but data comparing the two directly are limited. Aim The aim of this study is to evaluate the outcomes for hysteroscopic resection for the management of RPOC in comparison to current standard management techniques. Methods A literature search was conducted in September 2019 using MEDLINE, Scopus, The Cochrane Library and Web of Science. The key search terms were ‘hysteroscopy’/‘hysteroscopic resection’ and ‘retained products of conception’/‘RPOC’. Both prospective and retrospective studies were included. A total of 19 studies were included (n = 2314). Due to a critical risk of bias in all studies with a comparison arm, a meta‐analysis was not performed. Meta‐analysis techniques were still used to provide summary estimates for primary and secondary outcomes, including conception rate, time to conception, live birth rate, intrauterine adhesions (IUAs), surgical complications and future pregnancy complications. Results The overall conception rate for hysteroscopic resection was 81.1% (live birth rate 87.3%) compared to 65.4% for non‐hysteroscopic management (live birth rate 93.8%). After hysteroscopic resection the overall complication rate was 1.9% and the IUA rate was 6.8%. Conclusions Due to the poor quality and overall scarcity of comparative data, the question whether hysteroscopic resection is superior to traditional curettage for the management of RPOC remains unanswered. This review provides summary data, which will enable the design of adequately powered future studies.