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Abbreviated magnetic resonance imaging vs ultrasound for surveillance of hepatocellular carcinoma in high‐risk patients
Background & Aims We aimed to compare the performance of gadoxetic acid‐enhanced abbreviated MRI (AMRI)‐based surveillance and ultrasound‐only surveillance in high‐risk patients for hepatocellular carcinoma (HCC). Methods Prospectively recruited high‐risk patients (>5% annual risk of HCC) who...
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Published in: | Liver international 2022-08, Vol.42 (9), p.2080-2092 |
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Main Authors: | , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Background & Aims
We aimed to compare the performance of gadoxetic acid‐enhanced abbreviated MRI (AMRI)‐based surveillance and ultrasound‐only surveillance in high‐risk patients for hepatocellular carcinoma (HCC).
Methods
Prospectively recruited high‐risk patients (>5% annual risk of HCC) who underwent one to three rounds of complete gadoxetic acid‐enhanced MRI (CMRI) and ultrasound at 6‐months intervals were retrospectively analysed. AMRI consisted of diffusion‐weighted, T2‐weighted, and hepatobiliary phase imaging. The sensitivity, specificity, and accuracy of CMRI followed by AMRI (CAA), AMRI‐only (AAA), and ultrasound‐only (US) were compared using generalized estimating equations. Image quality was assessed.
Results
In 382 patients, HCC was diagnosed in 43 (11.3%), including 42 with early‐stage HCCs. The sensitivities of CAA (90.7%, 39/43) and AAA (86.0%, 37/43) were higher than US (27.9% [12/43]; P |
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ISSN: | 1478-3223 1478-3231 |
DOI: | 10.1111/liv.15110 |