Biological and Clinical Significance of Adaptive Evolution of Coronaviruses

RNA viral genomes are generally small genomes that rarely exceed 10 kb in size. [...]these genomes are characterized by high mutation rates (typically, 10−4/base/replication cycle) since the viral polymerases (i.e., RNA-dependent RNA polymerase and reverse transcriptase) are prone to misincorporatio...

Full description

Saved in:

Bibliographic Details
Published in:	Life (Basel, Switzerland) Switzerland), 2021-10, Vol.11 (11), p.1129
Main Authors:	Beloukas, Apostolos, Rampias, Theodoros
Format:	Article
Language:	English
Subjects:	Adaptation Binding Biological evolution Clinical trials Coronaviruses COVID-19 COVID-19 vaccines Disease transmission DNA-directed RNA polymerase Editing Epidemiology Evolution Evolution & development Genes Genetic diversity Genetic engineering Genomes Genomics Infections Medical research Mutation Mutation rates n/a Natural selection Pandemics Polyadenine Polyadenylation Population studies Positive selection Proofreading Proteins Recombination Replication RNA polymerase RNA-binding protein RNA-directed DNA polymerase RNA-directed RNA polymerase Severe acute respiratory syndrome coronavirus 2 Viral diseases Viruses
Citations:	Items that this one cites
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!