Pitfalls in Interpretation of PET/CT in the Chest

Whole body positron emission tomography (PET)/computed tomography (CT) imaging with [18F]-fluoro-2-deoxy-D-glucose (FDG) is widely used in oncologic imaging. In the chest, common PET/CT applications include the evaluation of solitary pulmonary nodules, cancer staging, assessment of response to thera...

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Bibliographic Details
Published in:Seminars in ultrasound, CT, and MRI CT, and MRI, 2021-12, Vol.42 (6), p.588-598
Main Authors: Strange, Chad, Shroff, Girish S., Truong, Mylene T., Rohren, Eric M.
Format: Article
Language:English
Subjects:
Fluorodeoxyglucose F18
Humans
Neoplasm Staging
Positron Emission Tomography Computed Tomography
Thorax - diagnostic imaging
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Summary:Whole body positron emission tomography (PET)/computed tomography (CT) imaging with [18F]-fluoro-2-deoxy-D-glucose (FDG) is widely used in oncologic imaging. In the chest, common PET/CT applications include the evaluation of solitary pulmonary nodules, cancer staging, assessment of response to therapy, and detection of residual or recurrent disease. Knowledge of the technical artifacts and potential pitfalls that radiologists may encounter in the interpretation of PET/CT in the thorax is important to avoid misinterpretation and optimize patient management. This article will review pitfalls in the interpretation of PET/CT in the chest related to technical factors, physiologic uptake, false positive findings, false negative findings, and iatrogenic conditions.
ISSN:0887-2171
1558-5034
DOI:10.1053/j.sult.2021.04.017