Postoperative anti‐inflammatory efficacy of 2% saline rinses and a herbal‐ mouthwash after non‐surgical periodontal therapy for the management of periodontal inflammation in young adults with chlorhexidine allergy: A randomized controlled trial

• Published in: International journal of dental hygiene 2022-05, Vol.20 (2), p.408-414
• Main Authors: Al‐Zawawi, Abeer S., Shaheen, Marwa Y., Divakar, Darshan Devang, Aldulaijan, Hajer A., Basudan, Amani M.
• Format: Article
• Language: English
• Subjects: Allergies; Anti-Infective Agents, Local - therapeutic use; Anti-Inflammatory Agents - therapeutic use; Bone loss; Chlorhexidine; Chlorhexidine - therapeutic use; Clinical trials; Dental Plaque - drug therapy; Gingival index; herbal mouthwash; Humans; Hypersensitivity - drug therapy; Inflammation; Inflammation - drug therapy; Mouthwashes; Mouthwashes - therapeutic use; non‐surgical periodontal therapy; Patients; periodontal inflammation; Plaque index; salt water; Statistical analysis; Toothbrushing; Young Adult; Young adults
• ISSN: 1601-5029; 1601-5037
• DOI: 10.1111/idh.12583

Aim The present randomized controlled trial assessed the postoperative anti‐inflammatory efficacy of 2% saline rinses (SR) and a herbal‐ mouthwash (HMW) after non‐surgical periodontal therapy (NSPT) for the management of periodontal inflammation in patients with chlorhexidine (CHX) allergy. Materials and Methods Patients with periodontal inflammation with and without self‐reported CHX allergy were included. All patients underwent non‐surgical periodontal therapy (NSPT). Patients were randomly divided into three groups. In the SR and HMW groups, 2% SR and a HMW, respectively, were prescribed. In Group 3 (CHX‐group), patients without CHX allergy were included and were prescribed 0.12% CHX. In all groups, plaque index (PI), gingival index (GI), probing depth (PD), clinical attachment loss (AL), and marginal bone loss were measured at baseline. Clinical periodontal parameters were re‐assessed at 6‐weeks’ follow‐up. p