Predictors of premature discontinuation and prevalence of dropouts from a pulmonary rehabilitation program in patients with chronic obstructive pulmonary disease

To date, very little is known about the risk factors that contribute to premature discontinuation (dropout) from pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary disease (COPD). We examined prevalence and predictors of premature discontinuation in patients who participate...

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Bibliographic Details
Published in:Respiratory medicine 2022-03, Vol.193, p.106742-106742, Article 106742
Main Authors: Yohannes, Abebaw Mengistu, Casaburi, Richard, Dryden, Sheila, Hanania, Nicola Alexander
Format: Article
Language:English
Subjects:
Aged
Anxiety
COPD
Depression
Dropout
Dyspnea - complications
Dyspnea - etiology
Exercise Tolerance
Female
Forced Expiratory Volume
Humans
Male
Predictors
Prevalence
Pulmonary Disease, Chronic Obstructive
Pulmonary rehabilitation
Quality of Life
Surveys and Questionnaires
Treatment Outcome
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Summary:To date, very little is known about the risk factors that contribute to premature discontinuation (dropout) from pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary disease (COPD). We examined prevalence and predictors of premature discontinuation in patients who participated in an eight week PR program. We analyzed a prospectively maintained data-base of patients with COPD who attended a PR program from 2013 to 2019. We included patients 40 years or older with forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) ratio less than 0.7. Subjects were assigned completers or non-completers based on whether they completed the 8-week PR program. Quality of life was measured using the St-George's Respiratory Questionnaire (SGRQ), anxiety using the Anxiety Inventory for Respiratory disease (AIR), dyspnea using the modified Medical Research Council (mMRC) scale, and exercise capacity using the Incremental Shuttle Walk Test (ISWT). Nine hundred nighty three COPD patients (mean age = 70.82 years, FEV1 = 59.21% predicted, 51% male) entered the PR program. Of these, 259 (26%) discontinued PR prematurely and 139 (53%) were male. Compared with completers, non-completers had elevated symptoms of dyspnea and anxiety, had reduced exercise tolerance, were younger, and had poorer quality of life at entry (all p 
ISSN:0954-6111
1532-3064
DOI:10.1016/j.rmed.2022.106742