Can Insulin and Glucose Dynamics Bring Us Closer to Precision Dietary Management of Obesity?

Precision medicine using biomarkers to select the most effective and safe treatment options has been implemented for several diseases and conditions, and there is accumulating evidence that it also should be applied for the management of obesity. Weight gain and obesity are considered to develop as...

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Bibliographic Details
Published in:The Journal of nutrition 2022-03, Vol.152 (3), p.649-650
Main Authors: Hjorth, Mads F, Astrup, Arne
Format: Article
Language:English
Subjects:
Adult
Biomarkers
Body Composition
Body Mass Index
Carbohydrates
Diet
Environmental factors
Epigenetics
Glucose
Humans
Insulin
Insulin - metabolism
Insulin Secretion
Nutrition
Obesity
Precision medicine
Proteins
Satiety
Weight control
Weight Loss
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Summary:Precision medicine using biomarkers to select the most effective and safe treatment options has been implemented for several diseases and conditions, and there is accumulating evidence that it also should be applied for the management of obesity. Weight gain and obesity are considered to develop as an interaction between susceptible genes, epigenetic influence, and environmental factors where diet composition may play a pivotal role. The importance of protein for satiety and weight control has been known for a decade but the role of fats versus carbohydrates has been debated for decades. Most research within precision dietary management of obesity is focusing on carbohydrates, but it is important to note that reducing the carbohydrate content of a diet most often increases the fat content of the diet accordingly [as protein content is normally rather fixed between 15% and 20% of energy (%E)]
ISSN:0022-3166
1541-6100
DOI:10.1093/jn/nxac001