Pomegranate juice, but not an extract, confers a lower glycemic response on a high–glycemic index food: randomized, crossover, controlled trials in healthy subjects

Low–glycemic index diets have demonstrated health benefits associated with a reduced risk of developing type 2 diabetes. We tested whether pomegranate polyphenols could lower the glycemic response of a high–glycemic index food when consumed together and the mechanism by which this might occur. We co...

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Bibliographic Details
Published in:	The American journal of clinical nutrition 2017-12, Vol.106 (6), p.1384-1393
Main Authors:	Kerimi, Asimina, Nyambe-Silavwe, Hilda, Gauer, Julia S, Tomás-Barberán, Francisco A, Williamson, Gary
Format:	Article
Language:	English
Subjects:	Acarbose acute effects Adult alpha-amylase Animals Area Under Curve Beverages Blood blood glucose Blood Glucose - metabolism Blood levels Bread breads Caco-2 Cells carbohydrate digestion Citric acid clinical nutrition Cross-Over Studies Diabetes Diabetes mellitus Diet Dietary supplements Double-Blind Method drugs Fruit Fruit and Vegetable Juices Fruit juices fruits Gastrointestinal Microbiome Glucose Glucose transport Glucose transporter Glucose Transporter Type 2 - metabolism glucose transporters glycemic effect Glycemic index Glycemic Index - drug effects Glycemic Load - drug effects Hep G2 Cells Humans Hydrolyzable Tannins - pharmacology Hypoglycemic Agents - pharmacology Indexing Intestinal microflora intestinal microorganisms Lythraceae - chemistry Metabolism Metabolites Microbiota Microorganisms noninsulin-dependent diabetes mellitus Nutrient deficiency Oocytes pH effects Plant Preparations - pharmacology polyphenol Polyphenols Polyphenols - pharmacology pomegranate juice pomegranates Postprandial Period Randomization Risk assessment Risk reduction starch Sugar Xenopus Young Adult α-Amylase
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