A Practically Unified Electrochemical Strategy for Ni-Catalyzed Decarboxylative Cross-Coupling of Aryl Trimethylammonium Salts

By merging electrocatalysis and nickel catalysis, a unified strategy has been successfully applied to achieve the decarboxylative cross-coupling of four types of α-oxocarboxylic acids and their derivatives with aryl trimethylammonium salts under mild conditions. Our strategy provides a practical way...

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Published in:Organic letters 2022-03, Vol.24 (11), p.2137-2142
Main Authors: Kong, Xianqiang, Chen, Yiyi, Chen, Xiaohui, Lu, Zheng-Xuan, Wang, Wei, Ni, Shao-Fei, Cao, Zhong-Yan
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cited_by cdi_FETCH-LOGICAL-a345t-980dabd45827e9fd17339f13c6fa59133c98c0fe0b6b54b8c23830491d1fe1303
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container_end_page 2142
container_issue 11
container_start_page 2137
container_title Organic letters
container_volume 24
creator Kong, Xianqiang
Chen, Yiyi
Chen, Xiaohui
Lu, Zheng-Xuan
Wang, Wei
Ni, Shao-Fei
Cao, Zhong-Yan
description By merging electrocatalysis and nickel catalysis, a unified strategy has been successfully applied to achieve the decarboxylative cross-coupling of four types of α-oxocarboxylic acids and their derivatives with aryl trimethylammonium salts under mild conditions. Our strategy provides a practical way for preparing aryl ketones, amides, esters, or aldehydes.
doi_str_mv 10.1021/acs.orglett.2c00408
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title A Practically Unified Electrochemical Strategy for Ni-Catalyzed Decarboxylative Cross-Coupling of Aryl Trimethylammonium Salts
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