Ruthenium pincer complex-catalyzed heterocycle compatible alkoxycarbonylation of alkyl iodides: substrate keeps the catalyst active

The electron pair of the heteroatom in heterocycles will coordinate with metal catalysts and decrease or even inhibit their catalytic activity consequently. In this work, a pincer ruthenium-catalyzed heterocycle compatible alkoxycarbonylation of alkyl iodides has been developed. Benefitting from the...

Full description

Saved in:
Bibliographic Details
Published in:Chemical science (Cambridge) 2022-02, Vol.13 (8), p.2481-2486
Main Authors: Ai, Han-Jun, Yuan, Yang, Wu, Xiao-Feng
Format: Article
Language:English
Subjects:
Catalysts
Catalytic activity
Chemistry
Compatibility
Indoles
Iodides
Morpholine
Pyrazole
Ruthenium
Substrates
Thiophenes
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The electron pair of the heteroatom in heterocycles will coordinate with metal catalysts and decrease or even inhibit their catalytic activity consequently. In this work, a pincer ruthenium-catalyzed heterocycle compatible alkoxycarbonylation of alkyl iodides has been developed. Benefitting from the pincer ligand, a variety of heterocycles, such as thiophenes, morpholine, unprotected indoles, pyrrole, pyridine, pyrimidine, furan, thiazole, pyrazole, benzothiadiazole, and triazole, are compatible here. A pincer ruthenium-catalyzed heterocycle compatible alkoxycarbonylation of alkyl iodides has been developed.
ISSN:2041-6520
2041-6539
DOI:10.1039/d1sc06581e