Expansion of GARP-Expressing CD4+CD25−FoxP3+ T Cells and SATB1 Association with Activation and Coagulation in Immune Compromised HIV-1-Infected Individuals in South Africa

Although antiretroviral treatment lowers the burden of human immunodeficiency virus (HIV)-related disease, it does not always result in immunological recovery. This manifests as persistent chronic inflammation, immune activation or exhaustion that can promote the onset of co-morbidities. As the exac...

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Bibliographic Details
Published in:	Virologica Sinica 2021-10, Vol.36 (5), p.1133-1143
Main Authors:	Teer, Eman, Joseph, Danzil E., Dominick, Leanne, Glashoff, Richard H., Essop, M. Faadiel
Format:	Article
Language:	English
Subjects:	Amino acid sequence antiretroviral agents Antiretroviral drugs Biochemistry Biomedical and Life Sciences Biomedicine CD25 antigen CD38 antigen CD4 antigen CD8 antigen Coagulation Cross-Sectional Studies disease progression Flow cytometry Forkhead protein Forkhead Transcription Factors Foxp3 protein Glycoproteins HIV HIV infections HIV-1 Human immunodeficiency virus Humans Inflammation Interleukin 10 Interleukin 6 Lymphocyte Activation Lymphocytes Lymphocytes T Matrix Attachment Region Binding Proteins Medical Microbiology Microbial Genetics and Genomics Microbiology Oncology Plasma levels Research Article South Africa T-Lymphocytes, Regulatory viral load Virology
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