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Homing in on cognition with cross-sectional analysis of sarcopenia-related measurements: the SARCOG study
Background Cognitive impairment may cause significant decline in muscle function and physical performance via affecting the neuromotor control. Aim To investigate the relationship between cognition and sarcopenia-related parameters in middle-aged and older adults. Methods Demographic data and comorb...
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| Published in: | Aging clinical and experimental research 2022-05, Vol.34 (9), p.2149-2154 |
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| creator | Kara, Özgür Kara, Murat Kaymak, Bayram Kaya, Tuğçe Cansu Çıtır, Beyza Nur Durmuş, Mahmut Esad Durmuşoğlu, Esra Doğan, Yahya Tiftik, Tülay Turan, Gökhan Gürçay, Eda Analay, Pelin Ocak, Hasan Şener, Fatıma Edibe Özçakar, Levent |
| description | Background
Cognitive impairment may cause significant decline in muscle function and physical performance via affecting the neuromotor control.
Aim
To investigate the relationship between cognition and sarcopenia-related parameters in middle-aged and older adults.
Methods
Demographic data and comorbidities of adults ≥ 45-year-old were noted. The Mini-Mental State Examination (MMSE) was used to evaluate global cognitive function. Sonographic anterior midthigh muscle thickness, handgrip strength, chair stand test (CST) and gait speed were measured. The diagnosis of sarcopenia was established if low muscle mass was combined with low muscle function. Dynapenia was defined as low grip strength or increased CST duration.
Results
Among 1542 subjects (477 M, 1065 F), sarcopenia and dynapenia were detected in 22.6 and 17.2% of males, and 17.2 and 25.3% of females, respectively. Sarcopenic patients were older and had higher body mass index, higher frequencies of hypertension, diabetes mellitus and obesity. They had lower muscle thickness, grip strength in males only, CST performance in females only and gait speed than the other groups (all
p
|
| doi_str_mv | 10.1007/s40520-022-02145-5 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2666548810</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2712354504</sourcerecordid><originalsourceid>FETCH-LOGICAL-c375t-27f1826b8b7f19581a14f8448511565928749fcf0a8b1413871b31a20b2128263</originalsourceid><addsrcrecordid>eNp9kVFP2zAQx62JiXaML8ADssQLLxk-x05c3qpqwCSkSoM9W07qFKMkLr5EU7_9jrYbaA882D7f_e5Od3_GzkB8AyHKK1RCS5EJKemA0pn-xKZQksvkMDt6Z0_YF8RnIRTQ55hNcq1NTsEpC3exC_2ah57Hntdx3YchkPU7DE-8ThExQ1-_ulzLHV1bDMhjw9GlOm58H1yWfOsGv-Kddzgm3_l-wGs-PHn-MP-5WN5yHMbV9iv73LgW_enhPWG_br4_Lu6y--Xtj8X8PqvzUg-ZLBswsqhMRcZMG3CgGqOU0QC60DNpSjVr6kY4UwHNY0qocnBSVBIkJeYn7HJfd5Piy-hxsF3A2ret630c0cqiKLQyBgShF_-hz3FMNCRRJchcKy0UUXJP7daRfGM3KXQubS0I-yqE3QthSQi7E8JqSjo_lB6rzq_-pfzdPAH5HkAK9Wuf3np_UPYPq0ORaQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2712354504</pqid></control><display><type>article</type><title>Homing in on cognition with cross-sectional analysis of sarcopenia-related measurements: the SARCOG study</title><source>Springer Link</source><creator>Kara, Özgür ; Kara, Murat ; Kaymak, Bayram ; Kaya, Tuğçe Cansu ; Çıtır, Beyza Nur ; Durmuş, Mahmut Esad ; Durmuşoğlu, Esra ; Doğan, Yahya ; Tiftik, Tülay ; Turan, Gökhan ; Gürçay, Eda ; Analay, Pelin ; Ocak, Hasan ; Şener, Fatıma Edibe ; Özçakar, Levent</creator><creatorcontrib>Kara, Özgür ; Kara, Murat ; Kaymak, Bayram ; Kaya, Tuğçe Cansu ; Çıtır, Beyza Nur ; Durmuş, Mahmut Esad ; Durmuşoğlu, Esra ; Doğan, Yahya ; Tiftik, Tülay ; Turan, Gökhan ; Gürçay, Eda ; Analay, Pelin ; Ocak, Hasan ; Şener, Fatıma Edibe ; Özçakar, Levent</creatorcontrib><description>Background
Cognitive impairment may cause significant decline in muscle function and physical performance via affecting the neuromotor control.
Aim
To investigate the relationship between cognition and sarcopenia-related parameters in middle-aged and older adults.
Methods
Demographic data and comorbidities of adults ≥ 45-year-old were noted. The Mini-Mental State Examination (MMSE) was used to evaluate global cognitive function. Sonographic anterior midthigh muscle thickness, handgrip strength, chair stand test (CST) and gait speed were measured. The diagnosis of sarcopenia was established if low muscle mass was combined with low muscle function. Dynapenia was defined as low grip strength or increased CST duration.
Results
Among 1542 subjects (477 M, 1065 F), sarcopenia and dynapenia were detected in 22.6 and 17.2% of males, and 17.2 and 25.3% of females, respectively. Sarcopenic patients were older and had higher body mass index, higher frequencies of hypertension, diabetes mellitus and obesity. They had lower muscle thickness, grip strength in males only, CST performance in females only and gait speed than the other groups (all
p
< 0.05). Sarcopenic and dynapenic patients had similar MMSE scores which were lower than those of normal subjects (both
p
< 0.001). After adjusting for confounding factors, MMSE values were positively related with grip strength in females only, CST performance and gait speed (all
p
< 0.001); but not with muscle thickness in either gender.
Conclusion
Cognitive impairment may unfavorably affect muscle function and physical performance, but not muscle mass. Accordingly, its prompt management can help to decrease patient morbidity and mortality.</description><identifier>ISSN: 1720-8319</identifier><identifier>ISSN: 1594-0667</identifier><identifier>EISSN: 1720-8319</identifier><identifier>DOI: 10.1007/s40520-022-02145-5</identifier><identifier>PMID: 35583720</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Cognition & reasoning ; Cognitive ability ; Cross-sectional studies ; Gait ; Geriatrics/Gerontology ; Medicine ; Medicine & Public Health ; Muscle function ; Original Article ; Sarcopenia</subject><ispartof>Aging clinical and experimental research, 2022-05, Vol.34 (9), p.2149-2154</ispartof><rights>The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022</rights><rights>2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.</rights><rights>The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c375t-27f1826b8b7f19581a14f8448511565928749fcf0a8b1413871b31a20b2128263</citedby><cites>FETCH-LOGICAL-c375t-27f1826b8b7f19581a14f8448511565928749fcf0a8b1413871b31a20b2128263</cites><orcidid>0000-0003-0125-4865</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35583720$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kara, Özgür</creatorcontrib><creatorcontrib>Kara, Murat</creatorcontrib><creatorcontrib>Kaymak, Bayram</creatorcontrib><creatorcontrib>Kaya, Tuğçe Cansu</creatorcontrib><creatorcontrib>Çıtır, Beyza Nur</creatorcontrib><creatorcontrib>Durmuş, Mahmut Esad</creatorcontrib><creatorcontrib>Durmuşoğlu, Esra</creatorcontrib><creatorcontrib>Doğan, Yahya</creatorcontrib><creatorcontrib>Tiftik, Tülay</creatorcontrib><creatorcontrib>Turan, Gökhan</creatorcontrib><creatorcontrib>Gürçay, Eda</creatorcontrib><creatorcontrib>Analay, Pelin</creatorcontrib><creatorcontrib>Ocak, Hasan</creatorcontrib><creatorcontrib>Şener, Fatıma Edibe</creatorcontrib><creatorcontrib>Özçakar, Levent</creatorcontrib><title>Homing in on cognition with cross-sectional analysis of sarcopenia-related measurements: the SARCOG study</title><title>Aging clinical and experimental research</title><addtitle>Aging Clin Exp Res</addtitle><addtitle>Aging Clin Exp Res</addtitle><description>Background
Cognitive impairment may cause significant decline in muscle function and physical performance via affecting the neuromotor control.
Aim
To investigate the relationship between cognition and sarcopenia-related parameters in middle-aged and older adults.
Methods
Demographic data and comorbidities of adults ≥ 45-year-old were noted. The Mini-Mental State Examination (MMSE) was used to evaluate global cognitive function. Sonographic anterior midthigh muscle thickness, handgrip strength, chair stand test (CST) and gait speed were measured. The diagnosis of sarcopenia was established if low muscle mass was combined with low muscle function. Dynapenia was defined as low grip strength or increased CST duration.
Results
Among 1542 subjects (477 M, 1065 F), sarcopenia and dynapenia were detected in 22.6 and 17.2% of males, and 17.2 and 25.3% of females, respectively. Sarcopenic patients were older and had higher body mass index, higher frequencies of hypertension, diabetes mellitus and obesity. They had lower muscle thickness, grip strength in males only, CST performance in females only and gait speed than the other groups (all
p
< 0.05). Sarcopenic and dynapenic patients had similar MMSE scores which were lower than those of normal subjects (both
p
< 0.001). After adjusting for confounding factors, MMSE values were positively related with grip strength in females only, CST performance and gait speed (all
p
< 0.001); but not with muscle thickness in either gender.
Conclusion
Cognitive impairment may unfavorably affect muscle function and physical performance, but not muscle mass. Accordingly, its prompt management can help to decrease patient morbidity and mortality.</description><subject>Cognition & reasoning</subject><subject>Cognitive ability</subject><subject>Cross-sectional studies</subject><subject>Gait</subject><subject>Geriatrics/Gerontology</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Muscle function</subject><subject>Original Article</subject><subject>Sarcopenia</subject><issn>1720-8319</issn><issn>1594-0667</issn><issn>1720-8319</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp9kVFP2zAQx62JiXaML8ADssQLLxk-x05c3qpqwCSkSoM9W07qFKMkLr5EU7_9jrYbaA882D7f_e5Od3_GzkB8AyHKK1RCS5EJKemA0pn-xKZQksvkMDt6Z0_YF8RnIRTQ55hNcq1NTsEpC3exC_2ah57Hntdx3YchkPU7DE-8ThExQ1-_ulzLHV1bDMhjw9GlOm58H1yWfOsGv-Kddzgm3_l-wGs-PHn-MP-5WN5yHMbV9iv73LgW_enhPWG_br4_Lu6y--Xtj8X8PqvzUg-ZLBswsqhMRcZMG3CgGqOU0QC60DNpSjVr6kY4UwHNY0qocnBSVBIkJeYn7HJfd5Piy-hxsF3A2ret630c0cqiKLQyBgShF_-hz3FMNCRRJchcKy0UUXJP7daRfGM3KXQubS0I-yqE3QthSQi7E8JqSjo_lB6rzq_-pfzdPAH5HkAK9Wuf3np_UPYPq0ORaQ</recordid><startdate>20220518</startdate><enddate>20220518</enddate><creator>Kara, Özgür</creator><creator>Kara, Murat</creator><creator>Kaymak, Bayram</creator><creator>Kaya, Tuğçe Cansu</creator><creator>Çıtır, Beyza Nur</creator><creator>Durmuş, Mahmut Esad</creator><creator>Durmuşoğlu, Esra</creator><creator>Doğan, Yahya</creator><creator>Tiftik, Tülay</creator><creator>Turan, Gökhan</creator><creator>Gürçay, Eda</creator><creator>Analay, Pelin</creator><creator>Ocak, Hasan</creator><creator>Şener, Fatıma Edibe</creator><creator>Özçakar, Levent</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-0125-4865</orcidid></search><sort><creationdate>20220518</creationdate><title>Homing in on cognition with cross-sectional analysis of sarcopenia-related measurements: the SARCOG study</title><author>Kara, Özgür ; Kara, Murat ; Kaymak, Bayram ; Kaya, Tuğçe Cansu ; Çıtır, Beyza Nur ; Durmuş, Mahmut Esad ; Durmuşoğlu, Esra ; Doğan, Yahya ; Tiftik, Tülay ; Turan, Gökhan ; Gürçay, Eda ; Analay, Pelin ; Ocak, Hasan ; Şener, Fatıma Edibe ; Özçakar, Levent</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c375t-27f1826b8b7f19581a14f8448511565928749fcf0a8b1413871b31a20b2128263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Cognition & reasoning</topic><topic>Cognitive ability</topic><topic>Cross-sectional studies</topic><topic>Gait</topic><topic>Geriatrics/Gerontology</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Muscle function</topic><topic>Original Article</topic><topic>Sarcopenia</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kara, Özgür</creatorcontrib><creatorcontrib>Kara, Murat</creatorcontrib><creatorcontrib>Kaymak, Bayram</creatorcontrib><creatorcontrib>Kaya, Tuğçe Cansu</creatorcontrib><creatorcontrib>Çıtır, Beyza Nur</creatorcontrib><creatorcontrib>Durmuş, Mahmut Esad</creatorcontrib><creatorcontrib>Durmuşoğlu, Esra</creatorcontrib><creatorcontrib>Doğan, Yahya</creatorcontrib><creatorcontrib>Tiftik, Tülay</creatorcontrib><creatorcontrib>Turan, Gökhan</creatorcontrib><creatorcontrib>Gürçay, Eda</creatorcontrib><creatorcontrib>Analay, Pelin</creatorcontrib><creatorcontrib>Ocak, Hasan</creatorcontrib><creatorcontrib>Şener, Fatıma Edibe</creatorcontrib><creatorcontrib>Özçakar, Levent</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health Medical collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Aging clinical and experimental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kara, Özgür</au><au>Kara, Murat</au><au>Kaymak, Bayram</au><au>Kaya, Tuğçe Cansu</au><au>Çıtır, Beyza Nur</au><au>Durmuş, Mahmut Esad</au><au>Durmuşoğlu, Esra</au><au>Doğan, Yahya</au><au>Tiftik, Tülay</au><au>Turan, Gökhan</au><au>Gürçay, Eda</au><au>Analay, Pelin</au><au>Ocak, Hasan</au><au>Şener, Fatıma Edibe</au><au>Özçakar, Levent</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Homing in on cognition with cross-sectional analysis of sarcopenia-related measurements: the SARCOG study</atitle><jtitle>Aging clinical and experimental research</jtitle><stitle>Aging Clin Exp Res</stitle><addtitle>Aging Clin Exp Res</addtitle><date>2022-05-18</date><risdate>2022</risdate><volume>34</volume><issue>9</issue><spage>2149</spage><epage>2154</epage><pages>2149-2154</pages><issn>1720-8319</issn><issn>1594-0667</issn><eissn>1720-8319</eissn><abstract>Background
Cognitive impairment may cause significant decline in muscle function and physical performance via affecting the neuromotor control.
Aim
To investigate the relationship between cognition and sarcopenia-related parameters in middle-aged and older adults.
Methods
Demographic data and comorbidities of adults ≥ 45-year-old were noted. The Mini-Mental State Examination (MMSE) was used to evaluate global cognitive function. Sonographic anterior midthigh muscle thickness, handgrip strength, chair stand test (CST) and gait speed were measured. The diagnosis of sarcopenia was established if low muscle mass was combined with low muscle function. Dynapenia was defined as low grip strength or increased CST duration.
Results
Among 1542 subjects (477 M, 1065 F), sarcopenia and dynapenia were detected in 22.6 and 17.2% of males, and 17.2 and 25.3% of females, respectively. Sarcopenic patients were older and had higher body mass index, higher frequencies of hypertension, diabetes mellitus and obesity. They had lower muscle thickness, grip strength in males only, CST performance in females only and gait speed than the other groups (all
p
< 0.05). Sarcopenic and dynapenic patients had similar MMSE scores which were lower than those of normal subjects (both
p
< 0.001). After adjusting for confounding factors, MMSE values were positively related with grip strength in females only, CST performance and gait speed (all
p
< 0.001); but not with muscle thickness in either gender.
Conclusion
Cognitive impairment may unfavorably affect muscle function and physical performance, but not muscle mass. Accordingly, its prompt management can help to decrease patient morbidity and mortality.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>35583720</pmid><doi>10.1007/s40520-022-02145-5</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-0125-4865</orcidid></addata></record> |
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| subjects | Cognition & reasoning Cognitive ability Cross-sectional studies Gait Geriatrics/Gerontology Medicine Medicine & Public Health Muscle function Original Article Sarcopenia |
| title | Homing in on cognition with cross-sectional analysis of sarcopenia-related measurements: the SARCOG study |
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