Klotho expression in peripheral blood circulating cells is associated with vascular and systemic inflammation in atherosclerotic vascular disease

Cardiovascular disease is the leading cause of death worldwide. New therapeutic strategies are aimed to modulate the athero-inflammatory process that partially orchestrates underlying vascular damage. Peripheral blood circulating cells include different immune cells with a central role in the develo...

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Published in:Scientific reports 2022-05, Vol.12 (1), p.8422-14, Article 8422
Main Authors: Martín-Núñez, Ernesto, Pérez-Castro, Atteneri, Tagua, Víctor G., Hernández-Carballo, Carolina, Ferri, Carla, Pérez-Delgado, Nayra, Rodríguez-Ramos, Sergio, Cerro-López, Purificación, López-Castillo, Ángel, Delgado-Molinos, Alejandro, López-Tarruella, Victoria Castro, Arévalo-Gómez, Miguel A., González-Luis, Ainhoa, Martín-Olivera, Alberto, Morales-Estévez, Carmen Chaxiraxi, Mora-Fernández, Carmen, Donate-Correa, Javier, Navarro-González, Juan F.
Format: Article
Language:English
Subjects:
631/443/592/75/593/2100
631/443/7
Aging
Arteriosclerosis
Atherosclerosis
Atherosclerosis - genetics
Biomarkers
Blood & organ donations
Cadavers
Cardiovascular Diseases
Case-Control Studies
Cross-Sectional Studies
DNA methylation
DNMT1 protein
Gene expression
Glucuronidase - metabolism
Humanities and Social Sciences
Humans
Inflammation
Inflammation - genetics
Inflammation - metabolism
Interleukin 1
Interleukin 10
Klotho protein
Klotho Proteins
Lymphocytes
Macrophages
Methylation
Monocytes
multidisciplinary
Organ donors
Patients
Peripheral blood
Plaques
Science
Science (multidisciplinary)
Serum levels
Tumor Necrosis Factor-alpha - genetics
Tumor necrosis factor-α
Vascular diseases
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