Examination of micro-superficial lesions of up to 5 mm in size in the pharyngolaryngeal region

For low-grade intraepithelial neoplasia cases, pharyngolaryngeal lesions equal to or less than 5 mm in size do not generally progress to invasive carcinoma. However, micro-superficial lesions equal to or less than 5 mm that showed rapid growth have been recently encountered. This study aimed to iden...

Full description

Saved in:
Bibliographic Details
Published in:Journal of laryngology and otology 2023-07, Vol.137 (7), p.749-756
Main Authors: Ueda, T, Yumii, K, Urabe, Y, Chikuie, N, Takumida, M, Taruya, T, Kono, T, Hamamoto, T, Hattori, M, Oka, S, Tanaka, S, Ishino, T, Takeno, S
Format: Article
Language:English
Subjects:
Alcohol
Biopsy
Carcinoma in Situ - diagnostic imaging
Carcinoma in Situ - pathology
Carcinoma, Squamous Cell - diagnosis
Carcinoma, Squamous Cell - pathology
Cell differentiation
Classification
Coloration
Endoscopy
Esophageal cancer
Head & neck cancer
Humans
Lesions
Main Article
Narrow Band Imaging - methods
Patients
Predictive Value of Tests
Retrospective Studies
Society
Squamous cell carcinoma
Throat cancer
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:For low-grade intraepithelial neoplasia cases, pharyngolaryngeal lesions equal to or less than 5 mm in size do not generally progress to invasive carcinoma. However, micro-superficial lesions equal to or less than 5 mm that showed rapid growth have been recently encountered. This study aimed to identify the characteristics of preferential progression of lesions equal to or less than 5 mm in size. Gross findings, endoscopic findings and pathological results of 55 lesions measuring equal to or less than 5 mm in diameter were retrospectively reviewed to identify factors that distinguish squamous cell carcinoma or high-grade intraepithelial neoplasia from low-grade intraepithelial neoplasia or non-atypia lesions. The overall sensitivity, specificity, accuracy, and positive and negative predictive value of background colouration and intrapapillary capillary loop pattern in differentiation of squamous cell carcinoma or high-grade intraepithelial neoplasia from low-grade intraepithelial neoplasia or non-atypia lesions were all 100 per cent. Diagnosis based on background colouration and the intrapapillary capillary loop pattern on narrow-band imaging facilitates the pathological examination of lesions measuring equal to or less than 5 mm.
ISSN:0022-2151
1748-5460
DOI:10.1017/S0022215122001761