Second‐Generation Differential Tissue Harmonic Imaging Improves the Visualization of Renal Lesions

Objectives To compare to three nonlinear imaging techniques to conventional, grayscale ultrasound imaging of renal lesions. Methods Twenty adults with a known renal lesion and a body mass index >25 kg/m2 were enrolled in this prospective, institutional review board approved study. Each subject wa...

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Bibliographic Details
Published in:Journal of ultrasound in medicine 2023-04, Vol.42 (4), p.853-857
Main Authors: Forsberg, Flemming, Stanczak, Maria, Sinanan, Jesse K., Blackman, Rachel
Format: Article
Language:English
Subjects:
Adult
Body Mass Index
differential tissue harmonic imaging
Humans
Japan
Kidney - diagnostic imaging
nonlinear ultrasound imaging
Prospective Studies
renal lesions
tissue harmonic imaging
Ultrasonography - methods
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Summary:Objectives To compare to three nonlinear imaging techniques to conventional, grayscale ultrasound imaging of renal lesions. Methods Twenty adults with a known renal lesion and a body mass index >25 kg/m2 were enrolled in this prospective, institutional review board approved study. Each subject was imaged with an Aplio 500 scanner (Canon Medical Systems, Tokyo, Japan) using grayscale ultrasound, tissue harmonic imaging (THI) and two dual‐frequency, differential tissue harmonic imaging modes (DTHI and DTHI‐II, respectively). In total 184 images were scored by three independent and blinded observers for detail resolution, image quality, margin delineation, and depth penetration. Quantitative contrast‐to‐noise ratios (CNRs) were also calculated. Results Readers and CNR values showed that nonlinear imaging was superior to grayscale ultrasound (P 
ISSN:0278-4297
1550-9613
DOI:10.1002/jum.16071