Sepsis associated acute kidney injury in pediatric intensive care unit

Background We aimed to compare the acute kidney injury (AKI) incidence in pediatric septic shock patients according to the three different classifications. Methods We analyzed retrospectively 52 patients with severe sepsis between January 2019 and December 2019. Results While 21 patients have been d...

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Bibliographic Details
Published in:Therapeutic apheresis and dialysis 2023-02, Vol.27 (1), p.73-82
Main Authors: Ozkaya, Pinar Yazici, Taner, Sevgin, Ersayoğlu, Irem, Turan, Benay, Yildirim Arslan, Sema, Karapinar, Bülent, Kaplan Bulut, Ipek
Format: Article
Language:English
Subjects:
acute kidney injury
Acute Kidney Injury - diagnosis
Acute Kidney Injury - epidemiology
AKIN
Child
critical care
Humans
Intensive Care Units
Intensive Care Units, Pediatric
KDIGO
pRIFLE
Retrospective Studies
Risk Factors
sepsis
Sepsis - complications
Sepsis - epidemiology
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Summary:Background We aimed to compare the acute kidney injury (AKI) incidence in pediatric septic shock patients according to the three different classifications. Methods We analyzed retrospectively 52 patients with severe sepsis between January 2019 and December 2019. Results While 21 patients have been diagnosed with SA‐AKI according to the pRIFLE criteria, 20 children have been diagnosed according to the AKIN criteria, and 21 children have been diagnosed according to the KDIGO criteria. Older age, lower platelet count were determined as independently risk factor for SA‐AKI. Older age and higher PRISM score were associated with mortality. According to Canonical correlation coefficients, pRIFLE is the most successful classification to distinguish AKI state. The canonical correlation coefficients for pRIFLE, KDIGO, and AKIN were 0.817, 0.648, and 0.615, respectively. Conclusion Although AKI incidence was similar between the three classifications, pRIFLE was the most successful classification to distinguish AKI state.
ISSN:1744-9979
1744-9987
DOI:10.1111/1744-9987.13928