Association Between Hypercholesterolemia and Neck Pain in a Cross-sectional Population-based Study

Retrospective cross-sectional analysis. Degenerative changes are a major contributor to chronic neck pain. According to the vascular hypothesis of disk disease, atherosclerosis of the segmental arteries contributes to ischemia of the lumbar disks and resulting degenerative changes. Prior studies hav...

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Bibliographic Details
Published in:Spine (Philadelphia, Pa. 1976) Pa. 1976), 2023-01, Vol.48 (2), p.137-142
Main Authors: Ahorukomeye, Peter, Mahajan, Arushi, Du, Jerry Y., Yu, Charles C., Bhandutia, Amit K., Ahn, Nicholas U.
Format: Article
Language:English
Subjects:
Aged
Atherosclerosis - complications
Cardiovascular Diseases - complications
Cervical Vertebrae
Cross-Sectional Studies
Humans
Hypercholesterolemia - complications
Hypercholesterolemia - epidemiology
Intervertebral Disc Degeneration - epidemiology
Medicare
Neck Pain - etiology
Retrospective Studies
United States
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Summary:Retrospective cross-sectional analysis. Degenerative changes are a major contributor to chronic neck pain. According to the vascular hypothesis of disk disease, atherosclerosis of the segmental arteries contributes to ischemia of the lumbar disks and resulting degenerative changes. Prior studies have demonstrated an association between atherosclerotic risk factors and lumbar degenerative disease. Similarly, atherosclerosis may contribute to cervical disk degeneration. Cardiovascular disease is associated with the development of atherosclerosis, particularly in small vessels to the cervical spine. Hypercholesterolemia is a major contributor to the morbidity associated with cardiovascular disease. This study aims to examine the relationship between hypercholesterolemia and neck pain. Analysis was focused on the respondents to neck pain items of the standardized questionnaire. Odds ratios were calculated, and logistic regression analyses adjusted for demographic, education, and mental health conditions. There were 30,461 participants in the 2018 Medicare Expenditure Panel Survey (MEPS) survey. Of those, 1049 (3.4%) subjects responded to presence of a diagnosis of cervical disorders with neck pain. Mean age of respondents was 62.6±16.1. Overall prevalence of neck pain was 21.1%. Prevalence of neck pain was similar by age, sex, education level, and occupation ( P >0.05 for each). Neck pain was more prevalent in white race and lower total family income ( P
ISSN:0362-2436
1528-1159
DOI:10.1097/BRS.0000000000004485