Rehospitalisations, repeated aortic surgery, and death in initial survivors of surgery for Stanford type A aortic dissection and the significance of age - a nationwide registry-based cohort study

• Published in: European heart journal. Quality of care & clinical outcomes 2023-08, Vol.9 (5), p.520-528
• Main Authors: Gundlund, Anna, Køber, Lars, Høfsten, Dan E, Vester-Andersen, Morten, Pedersen, Maria W, Torp-Pedersen, Christian, Kragholm, Kristian, Søgaard, Peter, Smerup, Morten, Fosbøl, Emil L
• Format: Article
• Language: English
• Subjects: Age groups; Aged; Aorta, Thoracic - surgery; Aortic dissection; Aortic Dissection - surgery; Cohort Studies; Humans; Middle Aged; Patient Readmission; Registries; Surgery; Survivor
• ISSN: 2058-5225; 2058-1742
• DOI: 10.1093/ehjqcco/qcac061

Abstract Aims Describe and compare incidences across age groups of rehospitalization, repeated aortic surgery, and death in patients who survived surgery and hospitalization for type A aortic dissection. Methods and results From Danish nationwide registries, we identified patients hospitalized with Stanford type A aortic dissections (2006–2018). Survivors of hospitalization and surgery on the ascending aorta and/or aortic arch comprised the study population (n = 606, 36 (38.9%) 69 years old (group III)). During the first year, 62.5% were re-hospitalized and 1.4% underwent repeated aortic surgery with no significant differences across age groups (P = 0.68 and P = 0.39, respectively). Further, 5.9% died (group I: 3.0%, group II: 8.3%, group III: 7.4%, P = 0.04). After 10 years, 8.0% had undergone repeated aortic surgery (group I: 11.5%, group II: 8.5%, group III: 1.6%, P = 0.04) and 10.2% (group I), 17.0% (group II), and 22.2% (group III) had died (P = 0.01). Using multivariable Cox regression analysis, we described long-term outcomes comparing age groups. No age differences were found in one-year outcomes, while age > 69 years compared with age