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Rotavirus Leads Global Diarrhea Hospitalizations Among Young Children
Rotavirus was the leading cause of diarrhea requiring hospitalization among young children in 28 low- and middle-income countries despite the introduction of rotavirus vaccine, according to a study published in BMJ Global Health. Stool specimens were randomly selected from children with diarrhea and...
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Published in: | JAMA : the journal of the American Medical Association 2022-10, Vol.328 (15), p.1490-1490 |
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Main Author: | |
Format: | Article |
Language: | English |
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Online Access: | Get full text |
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Summary: | Rotavirus was the leading cause of diarrhea requiring hospitalization among young children in 28 low- and middle-income countries despite the introduction of rotavirus vaccine, according to a study published in BMJ Global Health. Stool specimens were randomly selected from children with diarrhea and tested for 16 causes. The samples came from 5465 children younger than 5 years who were hospitalized with diarrhea in a surveillance network of 33 hospitals in 2017 and 2018. Overall, the leading causes of diarrhea requiring hospitalization were rotavirus--which accounted for a third of cases--followed by Shigella, norovirus, and adenovirus types 40 and 41. Rotavirus was the leading cause of diarrhea in all regions except the Americas. Shigella was the leading cause in Central America, and norovirus was the leading cause in South America. By the end of 2017, rotavirus vaccines had been introduced in 21 of the 33 surveillance network sites. The proportion of hospitalizations attributable to rotavirus was about 21% in sites where rotavirus vaccine was introduced compared with about 42% in sites where it wasn't, study results indicated. |
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ISSN: | 0098-7484 1538-3598 |
DOI: | 10.1001/jama.2022.15474 |