The Clinical Impact of Other Primary Cancer in Patients Who Received Curative Treatment for Esophageal Cancer

Background/Aim: The present study evaluated the clinical impact of other metachronous or synchronous primary cancer (OPC) in patients who received curative treatment for esophageal cancer. Patients and Methods: The present study included 168 patients who underwent curative treatment for esophageal c...

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Bibliographic Details
Published in:Anticancer research 2022-11, Vol.42 (11), p.5635-5641
Main Authors: Aoyama, Toru, Maezawa, Yukio, Hara, Kentaro, Ju, Miwha, Komori, Keisuke, Tamagawa, Hiroshi, Tamagawa, Ayako, Kazama, Keisuke, Sawazaki, Sho, Hashimoto, Itaru, Kano, Kazuki, Cho, Haruhiko, Morita, Junya, Segami, Kenki, Ishiguro, Tetsushi, Sato, Tsutomu, Oshima, Takashi, Yukawa, Norio, Rino, Yasushi
Format: Article
Language:English
Subjects:
Cancer
Esophageal cancer
Esophagus
Medical prognosis
Multivariate analysis
Patients
Statistical analysis
Survival
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Summary:Background/Aim: The present study evaluated the clinical impact of other metachronous or synchronous primary cancer (OPC) in patients who received curative treatment for esophageal cancer. Patients and Methods: The present study included 168 patients who underwent curative treatment for esophageal cancer between 2005 and 2018. Prognosis and differences between the OPC status (metachronous/synchronous) and clinic pathological parameters was analyzed. Results: A total of 168 patients were included in this study. Forty patients were diagnosed with metachronous/synchronous OPC. When comparing the clinicopathological factors between the patients with and without OPC, the patients' background and postoperative clinical courses were very similar between the two groups. The 3- and 5-year overall survival rates in patients with esophageal cancer with OPC were 66.0% and 54.5%, respectively, while those in patients without OPC were 50.1% and 41.4%, respectively. There was no statistically significant difference in these rates (p=0.156). The OPC status was not included in the final multivariate analysis model. Conclusion: The OPC status was not found to be a prognostic factor for patients who received curative treatment for esophageal cancer. Therefore, it is not necessary to avoid performing curative treatment for esophageal cancer because of a patient's OPC status.
ISSN:0250-7005
1791-7530
DOI:10.21873/anticanres.16072