Comparison of thromboelastographic profiles in pediatric patients with congenital heart disease according to existence of cyanosis

Purpose Congenital heart disease (CHD) is divided into two groups according to cyanosis status. Cyanotic CHD has a low level of systemic oxygenation and is accompanied by increased erythropoiesis. We hypothesized that pediatric patients with CHD would exhibit different thromboelastographic profiles...

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Bibliographic Details
Published in:Journal of anesthesia 2023-02, Vol.37 (1), p.32-38
Main Authors: Kang, Woon-Seok, Hong, Seung-Wan, Oh, Chung-Sik, Yoon, Tae-Gyoon, Kim, Byung-Soo, Kwon, Yubi, Kim, Seong-Hyop
Format: Article
Language:English
Subjects:
Anesthesiology
Blood
Blood Coagulation Tests
Cardiac patients
Child
Children
Comparative analysis
Congenital heart disease
Critical Care Medicine
Cyanosis
Cyanosis - complications
Cyanosis - surgery
Diagnosis
Emergency Medicine
Genetic disorders
Health aspects
Heart Defects, Congenital - surgery
Heart diseases
Humans
Hypoxia - complications
Intensive
Medical examination
Medical research
Medicine
Medicine & Public Health
Medicine, Experimental
Original Article
Pain Medicine
Pediatrics
Prothrombin
Thrombelastography
Thrombin
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Summary:Purpose Congenital heart disease (CHD) is divided into two groups according to cyanosis status. Cyanotic CHD has a low level of systemic oxygenation and is accompanied by increased erythropoiesis. We hypothesized that pediatric patients with CHD would exhibit different thromboelastographic profiles according to their cyanosis status. Methods The study recruited 70 pediatric patients younger than 12 months who were undergoing surgery for CHD. Patients were allocated to the acyanotic group or cyanotic group after preoperative evaluations of their diagnosis and peripheral oxygen saturation in the operating room on room air. After inducing anesthesia, blood samples were collected. Hematologic and thromboelastographic profiles were evaluated. Results Demographic data were similar between groups. The thromboelastographic profiles did not differ significantly between the groups. Hematologic profiles generally did not significantly differ between groups, except hematocrit (Hct) was higher in the cyanotic group (41.7 ± 6.8% vs. 35.3 ± 5.3%, p  
ISSN:0913-8668
1438-8359
DOI:10.1007/s00540-022-03124-w