Impact of arterial location, pressure wave indicators, and measurement devices on arterial form factor and mean and central arterial pressure

Mean arterial pressure (MAP) is often estimated from cuff systolic (S) and diastolic (D) blood pressure (BP) using a fixed arterial form factor (FF, usually 0.33). If MAP is measured directly, a true FF can be calculated: FF = [MAP–DBP]/[SBP–DBP]. Because waveform shapes vary, true FF should also va...

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Bibliographic Details
Published in:Journal of human hypertension 2023-10, Vol.37 (10), p.891-897
Main Authors: Izzo, Joseph L., Mukhopadhyay, Debduti, Nagpal, Sagar, Osmond, Peter
Format: Article
Language:English
Subjects:
631/443/1338
692/699/75
Blood pressure
Epidemiology
Health Administration
Heart rate
Medicine
Medicine & Public Health
Public Health
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Summary:Mean arterial pressure (MAP) is often estimated from cuff systolic (S) and diastolic (D) blood pressure (BP) using a fixed arterial form factor (FF, usually 0.33). If MAP is measured directly, a true FF can be calculated: FF = [MAP–DBP]/[SBP–DBP]. Because waveform shapes vary, true FF should also vary and MAP accuracy will be affected. We studied factors affecting FF using radial tonography (SphygmoCor, n  = 376) or brachial oscillometry (Mobil-O-Graph, n  = 157) and to compare devices, 101 pairs were matched precisely for SBP and DBP. SphygmoCor brachioradial FF correlated strongly with central FF ( r 2  = 0.75), central augmentation index (cAI, r 2  = 0.39), and inversely with pulse pressure amplification (PPA) ratio ( r 2  = 0.44) [all p  
ISSN:1476-5527
0950-9240
1476-5527
DOI:10.1038/s41371-022-00791-w