Prenatal daily musical exposure is associated with enhanced neural representation of speech fundamental frequency: Evidence from neonatal frequency‐following responses

• Published in: Developmental science 2023-09, Vol.26 (5), p.e13362-n/a
• Main Authors: Arenillas‐Alcón, Sonia, Ribas‐Prats, Teresa, Puertollano, Marta, Mondéjar‐Segovia, Alejandro, Gómez‐Roig, María Dolores, Costa‐Faidella, Jordi, Escera, Carles
• Format: Article
• Language: English
• Subjects: Acoustics; Auditory evoked potentials; Auditory Perception; Auditory Stimuli; Brain; Cognitive Processes; Fetuses; Frequency; infants; Intonation; Language; Language Acquisition; Language Processing; Music; Neonatal care; Neonates; Neural coding; Neuroplasticity; newborns; Periodicity; plasticity; Preferences; Pregnancy; prenatal; Prenatal experience; Prenatal Influences; Singing; Speech; speech auditory brainstem response
• ISSN: 1363-755X; 1467-7687
• DOI: 10.1111/desc.13362

Fetal hearing experiences shape the linguistic and musical preferences of neonates. From the very first moment after birth, newborns prefer their native language, recognize their mother's voice, and show a greater responsiveness to lullabies presented during pregnancy. Yet, the neural underpinnings of this experience inducing plasticity have remained elusive. Here we recorded the frequency‐following response (FFR), an auditory evoked potential elicited to periodic complex sounds, to show that prenatal music exposure is associated to enhanced neural encoding of speech stimuli periodicity, which relates to the perceptual experience of pitch. FFRs were recorded in a sample of 60 healthy neonates born at term and aged 12–72 hours. The sample was divided into two groups according to their prenatal musical exposure (29 daily musically exposed; 31 not‐daily musically exposed). Prenatal exposure was assessed retrospectively by a questionnaire in which mothers reported how often they sang or listened to music through loudspeakers during the last trimester of pregnancy. The FFR was recorded to either a /da/ or an /oa/ speech‐syllable stimulus. Analyses were centered on stimuli sections of identical duration (113 ms) and fundamental frequency (F0 = 113 Hz). Neural encoding of stimuli periodicity was quantified as the FFR spectral amplitude at the stimulus F0. Data revealed that newborns exposed daily to music exhibit larger spectral amplitudes at F0 as compared to not‐daily musically‐exposed newborns, regardless of the eliciting stimulus. Our results suggest that prenatal music exposure facilitates the tuning to human speech fundamental frequency, which may support early language processing and acquisition. Research Highlights Frequency‐following responses to speech were collected from a sample of neonates prenatally exposed to music daily and compared to neonates not‐daily exposed to music. Neonates who experienced daily prenatal music exposure exhibit enhanced frequency‐following responses to the periodicity of speech sounds. Prenatal music exposure is associated with a fine‐tuned encoding of human speech fundamental frequency, which may facilitate early language processing and acquisition. Prenatal exposure to sound shapes the linguistic and musical preferences of neonates, but the neural underpinnings of this experience inducing plasticity remain elusive. We here recorded the frequency‐following response (FFR) to syllable speech stimuli in two groups of neonates,