Hypertension Requiring Medication Use: a Silent Predictor of Poor Outcomes After Pancreaticoduodenectomy

Background Although hypertension requiring medication (HTNm) is a well-known cardiovascular comorbidity, its association with postoperative outcomes is understudied. This study aimed to evaluate whether preoperative HTNm is independently associated with specific complications after pancreaticoduoden...

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Bibliographic Details
Published in:Journal of gastrointestinal surgery 2023-02, Vol.27 (2), p.328-336
Main Authors: Lin, Jackie J., Conroy, Patricia C., Romero-Hernandez, Fernanda, Yilma, Mignote, Feng, Jean, Hirose, Kenzo, Nakakura, Eric, Maker, Ajay V., Corvera, Carlos, Kirkwood, Kimberly, Alseidi, Adnan, Adam, Mohamed A.
Format: Article
Language:English
Subjects:
Adult
Chronic obstructive pulmonary disease
Comorbidity
Diabetes
Gastroenterology
Heart failure
Humans
Hypertension
Hypertension - complications
Hypertension - epidemiology
Male
Medicine
Medicine & Public Health
Obesity - complications
Original Article
Pancreatectomy - adverse effects
Pancreatic Fistula - etiology
Pancreaticoduodenectomy
Pancreaticoduodenectomy - adverse effects
Postoperative Complications - epidemiology
Postoperative Complications - etiology
Postoperative period
Pulmonary Disease, Chronic Obstructive - complications
Retrospective Studies
Risk Factors
Surgery
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Summary:Background Although hypertension requiring medication (HTNm) is a well-known cardiovascular comorbidity, its association with postoperative outcomes is understudied. This study aimed to evaluate whether preoperative HTNm is independently associated with specific complications after pancreaticoduodenectomy. Study Design Adults undergoing elective pancreaticoduodenectomy were included from the 2014–2019 NSQIP-targeted pancreatectomy dataset. Multivariable regression models compared outcomes between patients with and without HTNm. Endpoints included significant complications, any complication, unplanned readmissions, length of stay (LOS), clinically relevant postoperative pancreatic fistula (CR-POPF), and cardiovascular and renal complications. A subgroup analysis excluded patients with diabetes, heart failure, chronic obstructive pulmonary disease, estimated glomerular filtration rate from serum creatinine (eGFRCr) 
ISSN:1091-255X
1873-4626
DOI:10.1007/s11605-022-05577-6