Preliminary Experiments of In Situ Atomic Force Microscopy Observation of Hydroxyapatite Formation on Bioactive Glass Surface

This paper demonstrates the use of atomic force microscopy (AFM) to image the bioactivity of phosphate glasses that are well‐known to react rapidly in simulated body fluid. The present study demonstrates that the hydroxyapatite (HAP) crystalline layer found via AFM in the examined samples coincides...

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Bibliographic Details
Published in:Journal of the American Ceramic Society 2002-02, Vol.85 (2), p.487-489
Main Authors: Leonelli, Cristina, Lusvardi, Gigliola, Menabue, L., Tonelli, Massimo
Format: Article
Language:English
Subjects:
Applied sciences
bioceramics
Biological and medical sciences
Building materials. Ceramics. Glasses
cerium/cerium compounds
Chemical industry and chemicals
Exact sciences and technology
Glasses
hydroxyapatite
Medical sciences
Structure, analysis, properties
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Technology. Biomaterials. Equipments
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Summary:This paper demonstrates the use of atomic force microscopy (AFM) to image the bioactivity of phosphate glasses that are well‐known to react rapidly in simulated body fluid. The present study demonstrates that the hydroxyapatite (HAP) crystalline layer found via AFM in the examined samples coincides with that identified using scanning electron microscopy. Moreover, the effect of a notorious bacteriostatic cation—tetravalent cerium, Ce(IV)—on the kinetics of the HAP layer is investigated in CeO2‐doped bioactive glasses.
ISSN:0002-7820
1551-2916
DOI:10.1111/j.1151-2916.2002.tb00118.x