Therapeutic inertia during isotretinoin treatment of juvenile acne by dermatologists, paediatricians and general practitioners

Isotretinoin is an effective treatment for severe juvenile acne, but it appears to be underused in relation to the recommendations. Therapeutic inertia is defined as a failure to initiate or intensify treatment even when warranted by the recommendations. The aim of this study was to investigate ther...

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Bibliographic Details
Published in:Annales de dermatologie et de vénéréologie 2023-03, Vol.150 (1), p.39-45
Main Authors: Mahé, E., Werner, A., Cret, L., Salinier, C., Guellich, A., Maruani, A., Assathiany, R.
Format: Article
Language:English
Subjects:
Acne
Acne Vulgaris - drug therapy
Adolescent
Dermatologic Agents - therapeutic use
Dermatologists
Female
General Practitioners
Humans
Isotretinoin
Isotretinoin - therapeutic use
Juvenile
Middle Aged
Pediatricians
Therapeutic inertia
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Summary:Isotretinoin is an effective treatment for severe juvenile acne, but it appears to be underused in relation to the recommendations. Therapeutic inertia is defined as a failure to initiate or intensify treatment even when warranted by the recommendations. The aim of this study was to investigate therapeutic inertia among dermatologists (D), paediatricians (P), and general practitioners (GPs) in initiating isotretinoin for moderate-to-very severe juvenile acne. Data were collected using a questionnaire distributed to French physicians through medical societies via Internet. The questions explored the role in inertia of factors related to physicians, patients, parents, and the healthcare system, and evaluated barriers and facilitators to prescribing isotretinoin. In all, 768 physicians responded to the survey (528 D, 178P, and 61 GPs; mean age: 51 years; women: 78 %). Their responses revealed that 99 % of dermatologists felt comfortable prescribing isotretinoin, compared with 8 % and 15 % of paediatricians and GPs (p 
ISSN:0151-9638
DOI:10.1016/j.annder.2022.11.005