Towards functional improvement of motor disorders associated with cerebral palsy

Cerebral palsy is a lifelong neurodevelopmental condition arising from non-progressive disorders occurring in the fetal or infant brain. Cerebral palsy has long been categorised into discrete motor types based on the predominance of spasticity, dyskinesia, or ataxia. However, these motor disorders,...

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Bibliographic Details
Published in:Lancet neurology 2023-03, Vol.22 (3), p.229-243
Main Authors: Bekteshi, Saranda, Monbaliu, Elegast, McIntyre, Sarah, Saloojee, Gillian, Hilberink, Sander R, Tatishvili, Nana, Dan, Bernard
Format: Article
Language:English
Subjects:
Adult
Ataxia
Cerebral palsy
Cerebral Palsy - complications
Cerebral Palsy - therapy
Classification
Clinical medicine
Clinical trials
Communication
Developing countries
Dyskinesia
Dystonia
Epidemiology
Exercise
Fetuses
High income
Humans
Infant
LDCs
Life span
Medical imaging
Medical prognosis
Motor ability
Motor Disorders - complications
Movement disorders
Muscle Spasticity
Neurodevelopmental disorders
Neuroimaging
Paralysis
Pathophysiology
Physical activity
Rehabilitation
Spasticity
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Summary:Cerebral palsy is a lifelong neurodevelopmental condition arising from non-progressive disorders occurring in the fetal or infant brain. Cerebral palsy has long been categorised into discrete motor types based on the predominance of spasticity, dyskinesia, or ataxia. However, these motor disorders, muscle weakness, hypotonia, and impaired selective movements should also be discriminated across the range of presentations and along the lifespan. Although cerebral palsy is permanent, function changes across the lifespan, indicating the importance of interventions to improve outcomes in motor disorders associated with the condition. Mounting evidence exists for the inclusion of several interventions, including active surveillance, adapted physical activity, and nutrition, to prevent secondary and tertiary complications. Avenues for future research include the development of evidence-based recommendations, low-cost and high-quality alternatives to existing therapies to ensure universal access, standardised cerebral palsy registers to harmonise epidemiological and clinical information, improved adult screening and check-up programmes to facilitate positive lived experiences, and phase 3 trials for new interventions.
ISSN:1474-4422
1474-4465
DOI:10.1016/S1474-4422(23)00004-2