Association of type 2 diabetes with coronary risk factors, clinical presentation, angiography, coronary interventions and follow-up outcomes: A single centre prospective registry

• Published in: Diabetes & metabolic syndrome clinical research & reviews 2023-02, Vol.17 (2), p.102709-102709, Article 102709
• Main Authors: Gupta, Rajeev, Lodha, Sailesh, Sharma, Krishna Kumar, Sharma, Sanjeev K., Makkar, Jitender S., Bana, Ajeet, Natani, Vishnu, Kumar, Sumit, Bharati, Shilpa, Sharma, Samin K.
• Format: Article
• Language: English
• Subjects: ACC NCDR CAthPCI registry; Acute Coronary Syndrome - etiology; Coronary Angiography; Coronary angioplasty; Coronary Artery Disease - complications; Coronary Artery Disease - diagnosis; Coronary heart disease; Coronary intervention; Diabetes Mellitus, Type 2 - complications; Female; Follow-Up Studies; Humans; Hypertension - etiology; Male; Myocardial Infarction - etiology; Percutaneous Coronary Intervention - adverse effects; Prospective Studies; Registries; Renal Insufficiency, Chronic - etiology; Risk Factors; Treatment Outcome; Type 2 diabetes
• ISSN: 1871-4021; 1878-0334
• DOI: 10.1016/j.dsx.2023.102709

To determine variations in coronary artery disease (CAD) clinical presentation, interventions, and outcomes in patients with diabetes vs without, a prospective study was performed. Successive patients with predominantly acute coronary syndromes who underwent percutaneous coronary intervention (PCI) were enrolled from January 2018 to March 2021. Patients with diabetes were compared to those without diabetes to determine differences in clinical and angiographic features and outcomes. In-person and telephonic follow-up were performed. Primary outcome was cardiovascular death and co-primary were major adverse cardiovascular events (cardiovascular death, myocardial infarction, revascularization, stroke). Cox-proportional hazard ratios (HR) and 95% confidence intervals (CI) were calculated. 5181 patients (men 4139,women 1042) were enrolled. Acute coronary syndrome(ACS) was in 4917 (94.9%) and diabetes in 1987 (38.4%). Patients with diabetes were older (61.1 ± 9.6 vs 59.7 ± 11.5years), with more hypertension (71.1 vs 45.5%), chronic kidney disease (3.0 vs 1.7%), previous PCI (13.5 vs 11.0%), past coronary artery bypass graft surgery (4.9 vs 2.4%), non ST-elevation myocardial infarction (59.6 vs 51.6%) and triple vessel disease (20.3 vs 17.2%) (p