Comparative evaluation of gingival fibroblast growth on 3D‐printed and milled zirconia: An in vitro study

Purpose The purpose of this study was to analyze the fibroblast growth and proliferation on 3D‐printed zirconia in presence and absence of porosities. Material and methods A total of 40 bars (8 × 4 × 3) were included in this study. Thirty 3D‐printed and 10 milled zirconia samples were prepared. The...

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Bibliographic Details
Published in:Journal of prosthodontics 2024-01, Vol.33 (1), p.54-60
Main Authors: Zandinejad, Amirali, Khurana, Saumya, Liang, Yongxi, Liu, Xiaohua
Format: Article
Language:English
Subjects:
3D‐printed
Animals
Cell culture
Fibroblasts
fibroblasts attachment
Materials Testing
milled
Printing, Three-Dimensional
Rats
Scanning electron microscopy
Zirconia
Zirconium - pharmacology
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Summary:Purpose The purpose of this study was to analyze the fibroblast growth and proliferation on 3D‐printed zirconia in presence and absence of porosities. Material and methods A total of 40 bars (8 × 4 × 3) were included in this study. Thirty 3D‐printed and 10 milled zirconia samples were prepared. The 3D‐printed samples had different porosities, 0% (PZ0), 20% (PZ20), and 40% (PZ40) with 10 specimens in each group. Milled zirconia samples were used as the control (MZ). Rat gingival fibroblasts were cultured for 48 h, and the proliferation of fibroblasts on each sample in each group (n = 10) was determined by MTT assays. The differences among the four groups were compared by one‐way ANOVA. To test the significance of the observed differences between two groups, an unpaired Student's t‐test was applied. The significance level was set at p 
ISSN:1059-941X
1532-849X
DOI:10.1111/jopr.13650