An oracle predicts regulators of cell identity

A computational tool called CellOracle can predict how networks of genes interact to program cell identity during embryonic development. The tool should help to hone efforts to understand how development is regulated. A computational tool to identify developmental regulators.

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Published in:Nature (London) 2023-02, Vol.614 (7949), p.630-632
Main Author: Farrell, Jeffrey A.
Format: Article
Language:English
Subjects:
631/114
631/136
631/553
Amino acids
Blood
Computational Biology
Computer applications
CRISPR
Depletion
Embryos
Erythrocytes
Genes
Genetic engineering
Genetic modification
Humanities and Social Sciences
Hypotheses
multidisciplinary
Mutation
News And Views
Perturbation
Preprints
PU.1 protein
Science
Systems Biology
Transcription factors
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creator Farrell, Jeffrey A.
description A computational tool called CellOracle can predict how networks of genes interact to program cell identity during embryonic development. The tool should help to hone efforts to understand how development is regulated. A computational tool to identify developmental regulators.
doi_str_mv 10.1038/d41586-023-00251-6
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subjects 631/114
631/136
631/553
Amino acids
Blood
Computational Biology
Computer applications
CRISPR
Depletion
Embryos
Erythrocytes
Genes
Genetic engineering
Genetic modification
Humanities and Social Sciences
Hypotheses
multidisciplinary
Mutation
News And Views
Perturbation
Preprints
PU.1 protein
Science
Systems Biology
Transcription factors
title An oracle predicts regulators of cell identity
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