3D Finite Element Model of Human Ear with 3-Chamber Spiral Cochlea for Blast Wave Transmission from the Ear Canal to Cochlea

• Published in: Annals of biomedical engineering 2023-05, Vol.51 (5), p.1106-1118
• Main Authors: Bradshaw, John J., Brown, Marcus A., Jiang, Shangyuan, Gan, Rong Z.
• Format: Article
• Language: English
• Subjects: Biochemistry; Biological and Medical Physics; Biomechanics; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Biophysics; Blast Injuries; Bones; Chambers; Classical Mechanics; Cochlea; Computer applications; Displacement; Ear; Ear canal; Ear Canal - physiology; Ear, Middle - physiology; Entrances; Finite Element Analysis; Finite element method; Fluid-structure interaction; Hearing loss; Hearing protection; Humans; Inner ear; Mathematical models; Membranes; Middle ear; Military personnel; Original Article; Overpressure; Pressure; Temporal bone; Three dimensional models; Tympanic Membrane
• ISSN: 0090-6964; 1573-9686
• DOI: 10.1007/s10439-023-03200-6

Blast-induced auditory trauma is a common injury in military service members and veterans that leads to hearing loss. While the inner ear response to blast exposure is difficult to characterize experimentally, computational models have advanced to predict blast wave transmission from the ear canal to the cochlea; however, published models have either straight or spiral cochlea with fluid-filled two chambers. In this paper, we report the recently developed 3D finite element (FE) model of the human ear mimicking the anatomical structure of the 3-chambered cochlea. The model consists of the ear canal, middle ear, and two and a half turns of the cochlea with three chambers separated by the Reissner’s membrane (RM) and the basilar membrane (BM). The blast overpressure measured from human temporal bone experiments was applied at the ear canal entrance and the Fluent/Mechanical coupled fluid–structure interaction analysis was conducted in ANSYS software. The FE model-derived results include the pressure in the canal near the tympanic membrane (TM) and the intracochlear pressure at scala vestibuli, the TM displacement, and the stapes footplate (SFP) displacement, which were compared with experimentally measured data in human temporal bones. The validated model was used to predict the biomechanical response of the ear to blast overpressure: distributions of the maximum strain and stress within the TM, the BM displacement variation from the base to apex, and the energy flux or total energy entering the cochlea. The comparison of intracochlear pressure and BM displacement with those from the FE model of 2-chambered cochlea indicated that the 3-chamber cochlea model with the RM and scala media chamber improved our understanding of cochlea mechanics. This most comprehensive FE model of the human ear has shown its capability to predict the middle ear and cochlea responses to blast overpressure which will advance our understanding of auditory blast injury.