Development of postoperative velopharyngeal function in patients with cleft palate

• Published in: International journal of pediatric otorhinolaryngology 2023-08, Vol.171, p.111607-111607, Article 111607
• Main Authors: Sakran, Karim Ahmed, Zhang, Shiming, Chen, Nan, Yin, Jiayi, Alkebsi, Khaled, Elayah, Sadam Ahmed, Al-Rokhami, Remsh Khaled, Al-Watary, Mohammed Qasem, Telha, Wael, Al-Aroomi, Maged, Shi, Bing, Yin, Heng, Huang, Hanyao
• Format: Article
• Language: English
• Subjects: Cleft palate; Cleft Palate - surgery; Follow-up time; Humans; Logistic regression; Retrospective Studies; Treatment Outcome; Velopharyngeal function; Velopharyngeal Insufficiency - surgery
• ISSN: 0165-5876; 1872-8464
• DOI: 10.1016/j.ijporl.2023.111607

Patients with a cleft palate often experience a velopharyngeal dysfunction known as velopharyngeal insufficiency (VPI). The purpose of this study was to examine the development of velopharyngeal function (VPF) following primary palatoplasty and the factors that are linked to it. A retrospective study was conducted to examine the medical records of patients who had cleft palate, with or without cleft lip (CP ± L) and underwent palatoplasty at a Tertiary Affiliated Hospital between 2004 and 2017. Postoperative evaluation of VPF was conducted at two follow-up times (T1, T2) and was classified as either normal VPF, mild VPI, or moderate/severe VPI. The consistency of VPF evaluations between the two time points was then assessed, and patients were categorized into either the consistent or inconsistent group. The study collected and analyzed data on gender, cleft type, age at operation, follow-up duration, and speech records. The study included 188 patients with CP ± L. Out of these, 138 patients (73.4%) showed consistent VPF evaluations, while 50 patients (26.6%) showed inconsistent VPF evaluations. Among those with VPI at T1 (91 patients), 36 patients (39.6%) had normal VPF at T2. The rate of VPI decreased from 48.40% at T1 to 27.13% at T2, whereas the rate of normal VPF increased from 44.68% at T1 to 68.09% at T2. The consistent group had a significantly younger age at operation (2.90 ± 3.82 vs 3.68 ± 4.02), a longer duration of T1 (1.67 ± 0.97 vs 1.04 ± 0.59), and a lower comprehensive score of speech performance (1.86 ± 1.27 vs 2.60 ± 1.07) than the inconsistent group. It has been verified that there are changes in the development of VPF over time. Patients who underwent palatoplasty at a younger age were more likely to have confirmed VPF diagnosis at the first evaluation. The duration of follow-up was identified as a critical factor that affects the confirmation of VPF diagnosis.